Results 111 to 120 of about 21,828 (248)
Experimental Physiology, EarlyView.Abstract Advanced age is the strongest risk factor for Alzheimer's disease and related dementias (ADRDs). Traumatic brain injury (TBI) has also been recognized as a risk factor for ADRD, potentially contributing to an earlier onset of the disease. Thus, elucidating the mechanisms underlying brain ageing and TBI is critical for developing strategies to ...
Tsubasa Tomoto +3 more
wiley +1 more source
Brain strain: Blood flow and metabolism in environmental extremes
Experimental Physiology, EarlyView.Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak +3 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Maintaining corticospinal tract function is crucial for voluntary movement. Exercise using high external loads/intensities is a promising intervention to promote adaptations to the corticospinal tract and improve physical function; however, such loads/intensities may not be tolerable or safe in populations with neurological disorders, motor ...
Kai T. Fox +5 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend During 10 h exposures to normobaric hypoxia exposure there was a selective leftward shift in ventilatory response to hyperoxic hypercapnic rebreathing, but not the cerebrovascular response. The key findings are that the resetting of the central chemoreflex to lower PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$ during early hypoxic ...
Holly Barclay +3 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Exercise‐induced increases in forearm venous plasma and serum brain‐derived neurotrophic factor (BDNF) are often assumed to be indicative of release from the brain. Sixteen healthy and physically fit adults (20–40 years old) were recruited to investigate whether exercise‐induced changes in forearm venous mature BDNF (mBDNF) and ...
Olga Tarassova +10 more
wiley +1 more source
Neuromuscular fatigability with repeated exercise in hypoxia: From single‐joint paradigms to sprints
The Journal of Physiology, EarlyView.Abstract figure legend Acute hypobaric or normobaric hypoxic exposure accelerates neuromuscular fatigability during repeated exercise. Indices of peripheral and central fatigue are not different at exhaustion in mild, moderate and severe hypoxia compared with normoxia, but task failure occurs earlier.
Luca Ruggiero +5 more
wiley +1 more source
Effects of online motor cortex transcranial ultrasound stimulation on interhemispheric inhibition
The Journal of Physiology, EarlyView.Abstract figure legend The present study investigated the online effect of primary motor cortex (M1) transcranial ultrasound stimulation (TUS) on interhemispheric inhibition (IHI) from the sonicated M1 to the contralateral M1 and on the contralateral M1 excitability.
Yanqiu Wang +6 more
wiley +1 more source
Neuropsychiatric Disease and Treatment, 2018 Ana Lusicic,1 Koen RJ Schruers,2 Stefano Pallanti,3,4 David J Castle5,6 1PACE Clinic, Orygen Youth Health, Melbourne, VIC, Australia; 2Research Institute for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands; 3Institute ...
Lusicic A +3 more
doaj
The Journal of Physiology, EarlyView.Abstract figure legend Schematic overview of the 5 day lower‐limb motor skill learning protocol combining ankle visuomotor practice with transcranial direct current stimulation (tDCS). Participants were allocated to motor skill practice with active tDCS over the leg representation of primary motor cortex (SKILL‐STIM), motor skill practice with sham ...
August Lomholt Kvistad +5 more
wiley +1 more source
Psychiatric Research and Clinical Practice, EarlyView.Objective This study evaluated whether intramuscular (IM) ketamine is non‐inferior to intranasal (IN) esketamine for treatment‐resistant depression (TRD) and assessed differences in safety and healthcare costs. Methods In a retrospective, observational sequential cohort at the VA San Diego, 179 Veterans with TRD received eight treatments of either IN ...
Kush V. Bhatt +12 more
wiley +1 more source