Results 81 to 90 of about 22,808 (183)

Re‐Emergent Postural Tremor Without Clinical Resting Tremor in Parkinson's Disease—A Case Report

Movement Disorders Clinical Practice, EarlyView.
Kevin R.E. van den Berg, Rick C. Helmich
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Pharmacological and non‐pharmacological interventions for managing sleep disorders in children with cerebral palsy: A systematic review

Developmental Medicine &Child Neurology, EarlyView.
xxxxxx Aim To systematically review the effectiveness, safety, and economic evidence of pharmacological and non‐pharmacological interventions for sleep disorders in children with cerebral palsy (CP). Method Databases including MEDLINE, Embase, CENTRAL (the Cochrane Library), International Clinical Trials Registry Platform of the World Health ...
Nishant Jaiswal, Lizzie Fisher, Giorgio Ciminata, Ryan Mulholland, Anna Noel‐Storr, Lesley Nutton, Valerie Orr, Paul Eunson, Nicola J. Cooper, Alex Sutton, Olivia Wu, Terry Quinn   +11 more
wiley   +1 more source

Framework for headache management in pediatric patients with stroke and cerebrovascular lesions: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To present a practical, evidence‐based framework for the management of headache disorders in pediatric patients with prior stroke or underlying cerebral vascular lesions, with particular attention to safety and efficacy of pharmacologic and non‐pharmacologic therapies.
Allison C. Hyland, Samuel J. Belfer, Christine K. Fox, Samantha L. Irwin, Rachel Vassar, Ann Oh, Sruthi Ilangovan, Amy A. Gelfand   +7 more
wiley   +1 more source

Research Review: A scoping review exploring the needs, barriers, and facilitators to the collection of biological data in adolescence for mental health research

Journal of Child Psychology and Psychiatry, EarlyView.
Background There is increasing recognition of the challenge of representativeness in data, including economic, social, and ethnic diversity, in biological mental health research. This is a particular challenge in adolescence, where brain and body development are impacted by the environment.
Courtney Worrell, Camila Ribeiro Perez, Sorcha Alford, Rebecca Pollard, Luca Sforzini, Cole Sommeling, James Hotham, Amanda Rodney, Zara Sadiq, Hana Shah, Tyler Weetman, Gillian Brooks, Matthew R. Broome, Niyah Campbell, Nzinga Gardner, Seeromanie Harding, Anna Lavis, Rosemary R.C. McEachan, Valeria Mondelli, Craig Morgan, Kierra Morris, Chiara Nosarti, Talya Porat, David Ryan, Katy Shire, Anthony Woods, Carmine M. Pariante, CELEBRATE Youth Expert Working Group, Paola Dazzan, Rachel Upthegrove   +29 more
wiley   +1 more source

Frontal Lobe Epilepsy Presenting With Unilateral Eye Closure

Neurology and Clinical Neuroscience, EarlyView.
Yuki Mizumoto, Kazutoshi Konomatsu, Takafumi Kubota, Kazushi Ukishiro, Yosuke Kakisaka, Makoto Yoshida, Kazutaka Jin   +6 more
wiley   +1 more source

Motor Sequence Learning Under Sleep Deprivation

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep deprivation (SD) compromises declarative memory encoding and subsequent consolidation, yet its consequences for the acquisition of new motor skill learning remain unknown. Forty‐eight healthy adults underwent either one night of total SD or normal sleep and were tested the next morning using a multimodal approach combining psychomotor ...
Guillaume Digonet, Thomas Lapole, Juliette Gélébart, Jérémie Bouvier, Mélanie Prudent, Vincent Pialoux, Maxime Pingon, Emeric Stauffer, Ursula Debarnot   +8 more
wiley   +1 more source

The effect of repetitive transcranial magnetic stimulation on the Hamilton Depression Rating Scale-17 criterion in patients with major depressive disorder without psychotic features: a systematic review and meta-analysis of intervention studies

BMC Psychology
Aim In line with the publication of clinical information related to the therapeutic process of repetitive transcranial magnetic stimulation (rTMS) and the updating of relevant treatment guidelines, the present meta-analysis study was designed and ...
Elham Hassanzadeh, Ghobad Moradi, Modabber Arasteh, Yousef Moradi   +3 more
doaj   +1 more source