Results 81 to 90 of about 868,934 (253)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Public Relations Strategies and Blood Donation in Thailand: A Case Study of Blood Donors and Non-Donors

open access: yes, 2011
The study explores the relationship between public relations strategies regarding blood donation in Thailand and audience responses to blood donation on the part of blood donors and non-donors as a comparative case study in terms of a) demographics ...
Patama Satawedin (7596293)
core   +3 more sources

Prevalence of Transfusion Transmitted Infection in Replacement and Voluntary Blood Donor

open access: yesRADS Journal of Biological Research & Applied Science, 2013
The aim of this study is to present the status of transfusion –transmitted infections among the apparently healthy donors so as to increase the awareness of complications of blood transfusion and make the clinicians more vigilant with regard to ...
Syeda Kanwal Zehra   +3 more
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Clinical and epidemiological profile of blood donors with positive serology for viral hepatitis in southern Brazil

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2011
INTRODUCTION: Positive serological tests for hepatitis viruses B and C at blood banks are an important reason for blood deferral. Additionally, high residual risk for transfusing hepatitis-contaminated blood has been estimated in southern Brazil.
Luciana da Silveira   +5 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Ethics of Liver Transplantation With Living Donors

open access: yes, 1989
Singer and six University of Chicago physicians describe their approach to the unique ethical aspects of liver transplantation with parents as living donors.
Singer, Peter A.   +3 more
core   +1 more source

Seroprevalence of transfusion transmissible infections among blood donors by chemiluminescent assay in a tertiary care centre

open access: yesJournal of Infection in Developing Countries, 2018
Introduction: Blood transfusion is a life saving measure, but also carries risk of transfusion transmitted infections (TTIs). In spite of improved donor screening, risk of transmission of TTIs still remains a major concern.
Raja Sundaramoorthy   +5 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Seroprevalence, trends, and risk factors of Syphilis and HIV among family replacement blood donors; a hospital-based retrospective study (2015-2021)

open access: yes
This dataset supports a research that seeks to determine the seroprevalence, trend, and risk factors of Syphilis and HIV among family replacement blood ...
Osei-Boakye, Felix
core   +1 more source

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