Results 111 to 120 of about 1,173,714 (339)

Is God in the details? A reexamination of the Role of Relegion in Economic [PDF]

open access: yes
Barro and McCleary (2003) is a key research contribution in the new literature exploring the macroeconomic effects of religious beliefs. This paper represents an effort to evaluate the strength of their claims.
Andros Kourtelos   +2 more
core  

Replication ethics [PDF]

open access: yesFutures, 2019
Suppose some future technology enables the same consciously experienced human life to be repeated, identically or nearly so, N times, in series or in parallel. Is this roughly N times as valuable as enabling the same life once, because each life has value and values are additive?
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Is God in the Details? A Reexamination of the Role of Religion in Economic Growth [PDF]

open access: yes
Barro and McCleary (2003) is a key research contribution in the new literature exploring the macroeconomic effects of religious beliefs. This paper represents an effort to evaluate the strength of their claims.
Andros Kourtellos   +2 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

A Reproducible Analysis of Sequential Recommender Systems

open access: yesIEEE Access
Sequential Recommender Systems (SRSs) have emerged as a highly efficient approach to recommendation systems. By leveraging sequential data, SRSs can identify temporal patterns in user behaviour, significantly improving recommendation accuracy and ...
Filippo Betello   +6 more
doaj   +1 more source

The Heuristic Value of p in Inductive Statistical Inference

open access: yesFrontiers in Psychology, 2017
Many statistical methods yield the probability of the observed data – or data more extreme – under the assumption that a particular hypothesis is true. This probability is commonly known as ‘the’ p-value.
Joachim I. Krueger, Patrick R. Heck
doaj   +1 more source

Replication factories

open access: yesTrends in Cell Biology, 1994
During S phase, DNA replication begins at numerous sites throughout the genome. Textbooks would have us believe that each replication fork tracks along the immobile DNA until it runs into the adjacent fork, but recent results question this view. Various studies show that replication forks are concentrated in immobile 'factory' units throughout the ...
Hozák, P, Cook, P
openaire   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Parvovirus replication

open access: yesMicrobiological Reviews, 1990
The members of the family Parvoviridae are among the smallest of the DNA viruses, with a linear single-stranded genome of about 5 kilobases. Currently the family is divided into three genera, two of which contain viruses of vertebrates and a third containing insect viruses.
openaire   +2 more sources

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