Results 111 to 120 of about 3,159,718 (373)
Getting ready for DNA duplication
eLife, 2019 The discovery of a biomolecular condensate involved in DNA replication has wide-ranging implications.
Nina Y Yao, Michael E O'Donnell
doaj +1 more source
How to package the RNA of HIV-1
eLife, 2020 Interactions between viral RNA and the integrase enzyme are required for HIV-1 particles to become infectious, a process that can be disrupted through multiple mechanisms.
Alex Kleinpeter, Eric O Freed
doaj +1 more source
Host Factors in Coronavirus Replication
Current Topics in Microbiology and Immunology, 2017 Coronaviruses are pathogens with a serious impact on human and animal health. They mostly cause enteric or respiratory disease, which can be severe and life threatening, e.g., in the case of the zoonotic coronaviruses causing severe acute respiratory ...
Adriaan H. de Wilde +3 more
semanticscholar +1 more source
Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution
FEBS Letters, EarlyView.The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai +2 more
wiley +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Proteomic data on the nuclear interactome of human MCM9
Data in Brief, 2016 We present data relating to the interactome of MCM9 from the nuclei of human cells. MCM9 belongs to the AAA+ superfamily, and contains an MCM domain and motifs that may confer DNA helicase activity.
James R.A. Hutchins +6 more
doaj +1 more source
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
The Replication Database: Documenting the Replicability of Psychological Science [PDF]
Journal of Open Psychology DataIn psychological science, replicability—repeating a study with a new sampleachieving consistent results (Parsons et al., 2022)—is critical for affirming the validity of scientific findings. Despite its importance, replication efforts are few and far between in psychological science with many attempts failing to corroborate past findings. This scarcity,
Lukas Röseler +96 more
openaire +10 more sources
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
A Highly Available Cluster of Web Servers with Increased Storage Capacity [PDF]
, 2006 Ponencias de las Decimoséptimas Jornadas de Paralelismo de la Universidad de Castilla-La Mancha celebradas el 18,19 y 20 de septiembre de 2006 en AlbaceteWeb servers scalability has been traditionally solved by improving software elements or increasing ...
Carretero Pérez, Jesús +4 more
core +2 more sources