Results 111 to 120 of about 1,158,325 (299)

Guanylate-binding protein 5 antagonizes viral glycoproteins independently of furin processing

mBio
Guanylate-binding protein (GBP) 5 is an interferon-inducible cellular factor with broad anti-viral activity. Recently, GBP5 has been shown to antagonize the glycoproteins of a number of enveloped viruses, in part by disrupting the host enzyme furin. Here
Hana Veler, Cheng Man Lun, Abdul A. Waheed, Eric O. Freed   +3 more
doaj   +1 more source

Replication of Resting State-Task Network Correspondence and Novel Findings on Brain Network Activation During Task fMRI in the Human Connectome Project Study [PDF]

, 2018
Lisa D. Nickerson
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Linking replication stress with heterochromatin formation [PDF]

, 2015
Ivaylo Nikolov, Angela Taddei
openalex   +1 more source

On the road to replication

EMBO Molecular Medicine, 2016
No description ...
openaire   +3 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Essential functions of inositol hexakisphosphate (IP6) in murine leukemia virus replication

mBio
We have investigated the function of inositol hexakisphosphate (IP6) and inositol pentakisphosphate (IP5) in the replication of murine leukemia virus (MLV).
Banhi Biswas, Kin Kui Lai, Harrison Bracey, Siddhartha A. K. Datta, Demetria Harvin, Gregory A. Sowd, Christopher Aiken, Alan Rein   +7 more
doaj   +1 more source

Characterization of Cell Lines Carrying Self-Replicating Hepatitis C Virus RNAs

, 2001
Thomas Pietschmann, Volker Lohmann, Gabriel Rütter, Katharina Kurpanek, Ralf Bartenschlager   +4 more
openalex   +1 more source

Inhibition of Avian Influenza A Virus Replication in Human Cells by Host Restriction Factor TUFM Is Correlated with Autophagy [PDF]

, 2017
Shu-Ming Kuo, Chi-Jene Chen, Shih‐Cheng Chang, Tzu-Jou Liu, Yi‐Hsiang Chen, Sheng‐Yu Huang, Shin‐Ru Shih   +6 more
openalex   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source