Results 201 to 210 of about 1,158,325 (299)

Auranofin attenuates TOPBP1-mediated ATR replication stress response and improves chemotherapeutic response in breast tumor models. [PDF]

J Clin Invest
Ma S, Han Y, Gu R, Chen Q, Guo Q, Yue Y, Cao C, Liu L, Yang Z, Qin Y, Yang Y, Zhang K, Liu F, Liu L, Yang N, Hao J, Yang J, Yao Z, Mao X, Shi L.   +19 more
europepmc   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Individual response to mTOR inhibition in delaying replicative senescence of mesenchymal stromal cells

, 2019
Eliane Antonioli, Natália Torres, Mário Ferretti, Carla de Azevedo Piccinato, Andréa L. Sertié   +4 more
openalex   +2 more sources

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Coronavirus nucleocapsid proteins: a multifaceted modulator in the innate immune evasion. [PDF]

Front Microbiol
Xiao Y, Song Z, Zhou L, Lu W, Fang W, Xu J, Li X.   +6 more
europepmc   +1 more source

SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis

, 2020
Alisa Atkins, Michelle J. Xu, Maggie Li, Nathaniel Rogers, Marina V. Pryzhkova, Philip W. Jordan   +5 more
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Propagation dynamics of Anaplasma marginale in a Brazilian tick cell line (RBME-6) derived from Rhipicephalus microplus. [PDF]

Rev Bras Parasitol Vet
Sanches GS, Castro-Santiago AC, Bassini-Silva R, Calchi AC, Simons SM, Mathias LA, Nunes PH, Machado RZ, André MR, Barros-Battesti DM.   +9 more
europepmc   +1 more source

APOBEC1 cytosine deaminase activity on single-stranded DNA is suppressed by replication protein A

, 2020
Lai Hong Wong, Frederick S. Vizeacoumar, Franco J. Vizeacoumar, Linda Chelico   +3 more
openalex   +1 more source