Results 41 to 50 of about 1,779,695 (298)

The Replication Crisis and Psychotherapy Efficacy Studies

open access: yesPsikoloji Çalışmaları, 2022
In the last ten years, the replication crisis, which has manifested itself and shaken the field of psychology profoundly, has led researchers in every subfield of psychology to reconsider research findings and general assumptions.
Kutlu Kağan Türkarslan
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The replication crisis and philosophy

open access: yesPhilosophy and the Mind Sciences, 2022
The replication crisis is perceived by many as one of the most significant threats to the reliability of research. Though reporting of the crisis has emphasized social science, all signs indicate that it extends to many other fields. This paper investigates the possibility that the crisis and related challenges to conducting research also extend to ...
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Irish contraception and crisis pregnancy [ICCP] study: a survey of the general population - summary [PDF]

open access: yes, 2004
The aim of the present study was to establish nationally representative data on current attitudes, knowledge and experience of contraception, crisis pregnancy and related services in Ireland.
McGee, Hannah   +3 more
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Mixed methods research of crisis pregnancy counselling and support services [PDF]

open access: yes, 2005
This study aimed to examine women’s experiences of crisis pregnancy counselling using both qualitative and quantitative methods. The study group comprised women with a crisis pregnancy who either decided on abortion or were continuing the pregnancy ...
Conlon, Catherine
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Crisis pregnancy and pregnancy decision making: An outline of influencing factors [PDF]

open access: yes, 2004
This document aims to review research literature in order to: • outline and describe the factors that have been demonstrated to affect the level and incidence of crisis pregnancy • examine the factors that affect a woman’s decision when faced with a ...
O’Keeffe, Stephanie
core  

Threats of a replication crisis in empirical computer science

open access: yesCommunications of the ACM, 2020
Research replication only works if there is confidence built into the results.
Cockburn, Andy   +3 more
openaire   +4 more sources

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