Results 211 to 220 of about 230,046 (255)
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Replication Initiation Point Mapping
Methods, 1997Replication in eukaryotes is bidirectional and semi-discontinuous. This asymmetry provides the basis for mapping the origin of bidirectional replication (OBR), which is the transition point from discontinuous to continuous synthesis. The regions of each DNA strand complementary to the leading strand or lagging strand can be measured by the methods of ...
S A, Gerbi, A K, Bielinsky
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REGULATION OF INITIATION OF DNA REPLICATION
Annual Review of Genetics, 1979INTRODUCTION 355 UNIQUENESS OF THE SITE OF INITIATION OF REPLICATION 357 STRUCTURE OF THE ORIGIN SITE 359 EVENTS AT THE INITIATION SITE . . . . 362 TRANSCRIPTIONAL ACTIVATION 365 DIRECTIONALITY OF REPLICATION 366 HOST FUNCTIONS REQUIRED FOR INITIATION 367 REPLICON-SPECIFIC INITIATION PROTEINS . . . . . . . . . . ...... ....... ....... .
R, Kolter, D R, Helinski
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Initiation of adenovirus DNA replication
Journal of Virology, 1980In an attempt to study the mechanism of initiation of adenovirus DNA replication, an assay was developed to investigate the pattern of DNA synthesis in early replicative intermediates of adenovirus DNA. By using wild-type virus-infected cells, it was possible to place the origin of adenovirus type 2 DNA replication within the terminal 350 to 500 base ...
T, Reiter +3 more
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Initiation of Viral DNA Replication
1988Publisher Summary This chapter focuses on the mechanisms involved in initiation of animal virus DNA replication. This step is of fundamental importance because it represents the central point of control of the replication process. Two of the best-characterized viruses, adenovirus and SV40, are discussed as examples of viruses that normally multiply ...
T J, Kelly, M S, Wold, J, Li
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Replication Initiative: Dangerous Logic
Science, 2012The comments voiced by some scientists in response to Brian Nosek's project to systematically replicate studies in social psychology (“Psychology's bold initiative,” S. Carpenter, News Focus, 30 March, p. [1558][1]) are deeply worrisome. Reluctance to replicate data in a given field of science because it might harm the field's public image among other ...
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2009
DNA replication is fundamental to cellular life on earth, and replication initiation provides the primary point of control over this process. Replication initiation in all organisms involves the interaction of initiator proteins with one or more origins of replication in the DNA, with subsequent regulated assembly of two replisome complexes at each ...
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DNA replication is fundamental to cellular life on earth, and replication initiation provides the primary point of control over this process. Replication initiation in all organisms involves the interaction of initiator proteins with one or more origins of replication in the DNA, with subsequent regulated assembly of two replisome complexes at each ...
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Replication Initiative: Prioritize Publication
Science, 2012The Open Science Collaboration's new platform for publishing the results of replicated experiments is commendable and indeed bold (“Psychology's bold initiative,” S. Carpenter, News Focus, 30 March, p. [1558][1]). However, as convenient and efficient as this platform may prove to be, it should not distract us from the need to revise and extend more ...
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Initiation of DNA Replication in the Archaea
2017Organisms within the archaeal domain of life possess a simplified version of the eukaryotic DNA replication machinery. While some archaea possess a bacterial-like mode of DNA replication with single origins of replication per chromosome, the majority of species characterized to date possess chromosomes with multiple replication origins.
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Replication Initiative: Beware Misinterpretation
Science, 2012Two new initiatives are exploring the reproducibility of findings within psychology (“Psychology's bold initiative,” S. Carpenter, News Focus, 30 March, p. [1558][1]). One approach provides an online outlet for replication attempts, regardless of success or failure.
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A turnstile for initiation of DNA replication
Trends in Cell Biology, 1991The progress of a cell through its growth cycle is a multifaceted process; so far we have seen only a glimpse of the complex interplay between the macromolecules performing and regulating the different steps involved. In most organisms, control mechanisms ensure that all chromosomal DNA sequences are replicated once, and only once, between two cell ...
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