Results 221 to 230 of about 247,162 (311)

The Telomeric Protein TRF2 Regulates Replication Origin Activity within Pericentromeric Heterochromatin. [PDF]

Life (Basel), 2021
Bauwens S, Lototska L, Koundrioukoff S, Debatisse M, Ye J, Gilson E, Mendez-Bermudez A.   +6 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

G-quadruplex as an essential structural element in cytomegalovirus replication origin. [PDF]

Nat Commun
Park D, Chung WC, Gong S, Ravichandran S, Lee GM, Han M, Kim KK, Ahn JH.   +7 more
europepmc   +1 more source

Bifidobacterium-Escherichia coli Shuttle Vector Series pKO403, with Temperature-Sensitive Replication Origin for Gene Knockout in Bifidobacterium. [PDF]

Microbiol Resour Announc, 2022
Altaib H, Ozaki Y, Kozakai T, Sakaguchi K, Nomura I, Suzuki T.   +5 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

ebv-sisRNA-3 contributes to the formation of G4-associated R-loop upstream of EBV lytic replication origin in latently infected cells. [PDF]

Cell Biosci
Wang B, Chung GTY, Shuai Y, Wu M, Ji D, Lung RWM, Chan YY, Liu MT, Kong EL, Hui SY, Leung HM, Wu Q, Chan MSA, Wang X, Zhu G, Yip KY, Kwok CK, Lo KW, Tsang CM.   +18 more
europepmc   +1 more source

Concerted actions of DnaA complexes with DNA-unwinding sequences within and flanking replication origin oriC promote DnaB helicase loading. [PDF]

J Biol Chem, 2022
Sakiyama Y, Nagata M, Yoshida R, Kasho K, Ozaki S, Katayama T.   +5 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

TEFM facilitates transition from RNA synthesis to DNA synthesis at H-strand replication origin of mtDNA. [PDF]

Commun Biol
Matsuda S, Nakayama M, Do Y, Ishiuchi T, Yagi M, Wanrooij S, Nakada K, Wei FY, Ichiyanagi K, Sasaki H, Kang D, Yasukawa T.   +11 more
europepmc   +1 more source

G-Quadruplexes Formation at the Upstream Region of Replication Origin (OriL) of the Pseudorabies Virus: Implications for Antiviral Targets. [PDF]

Viruses, 2021
Zhu Y, Liu W, Zhang C.
europepmc   +1 more source