Results 181 to 190 of about 7,567,038 (395)

Human SP-A1 (SFTPA1) variant-specific 3′ UTRs and poly(A) tail differentially affect the in vitro translation of a reporter gene

, 2010
Patricia Silveyra, Guirong Wang, Joanna Floros   +2 more
openalex   +2 more sources

Mutagenicity of Ochratoxin A and Its Hydroquinone Metabolite in the SupF Gene of the Mutation Reporter Plasmid Ps189 [PDF]

, 2012
Steven A. Akman, M. L. Adams, Doug Case, Gyungse Park, Richard A. Manderville   +4 more
openalex   +1 more source

Pathogen Response Genes Mediate Caenorhabditis elegans Innate Immunity

, 2012
Innate immunity is crucial in the response and defense against pathogens for invertebrates and vertebrates alike. The soil nematode Caenorhabditis elegans is a useful model to study the eukaryotic innate immune response to microbial pathogenesis.
Anthony, Hannah L.
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Visualizing mast cell migration to tumor sites using sodium iodide symporter of nuclear medicine reporter gene. [PDF]

Neoplasia, 2023
Oh SG, Choi JY, Lee JE, Jeon S, Lee BR, Son KH, Lee SB, An BS, Hwang DY, Kim SJ, Ha KT, Lee J, Jeon YH.   +12 more
europepmc   +1 more source

[Bioluminescent reporter genes].

Postepy biochemii, 2009
Reporter genes typically are used to monitor changes in transcriptional rate, which can vary quickly in response to a specific cellular event. Here we give background on bioluminescent reporters and assays and their uses in research.
openaire   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

The development and characterization of a stable Coxsackievirus A16 infectious clone with Nanoluc reporter gene. [PDF]

Front Microbiol, 2022
Yu R, Wang M, Liu L, Yan J, Fan J, Li X, Kang M, Xu J, Zhang X, Zhang S.   +9 more
europepmc   +1 more source

Looking Beyond the Drinking Water Directive: The Use of Reporter Gene Assays as an Added Tool for Effect-Based Monitoring of Polycyclic Aromatic Hydrocarbons (Pahs) and Polychlorinated Biphenyls (Pcbs) in Drinking Water Sources

, 2023
J.K.H. de Schepper, Tineke Slootweg, Peter Behnisch, Emiel Felzel, Corine J. Houtman   +4 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source