Results 181 to 190 of about 7,873,006 (309)

Development of a reporter gene method to measure the bioactivity of anti-CD38 × CD3 bispecific antibody. [PDF]

Antib Ther, 2021
Xiong H, Luo F, Zhou P, Yi J.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Reporter Gene Assay for Measuring the Biological Activity of PEGylated Recombinant Human Growth Hormone. [PDF]

Molecules
Hu S, Zhang X, Li Y, Li J, Wang Y, Liang C.   +5 more
europepmc   +1 more source

Reporter gene systems for the identification and characterization of cancer stem cells. [PDF]

World J Stem Cells, 2021
Salinas-Jazmín N, Rosas-Cruz A, Velasco-Velázquez M.   +2 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Enhanced ADCC Activity of a C-Terminal Lysine Variant of an IgG₁ Antibody Driven by N-Linked MAN5 Glycan Using a Reporter Gene Assay. [PDF]

Antibodies (Basel)
Hsieh MC, Dorofejeva K, Zhang J, Vy DL, Qian J, Matathia AM, Blanc T, Li CR, Parekh BS.   +8 more
europepmc   +1 more source

Covalent ¹⁸F-Radiotracers for SNAPTag: A New Toolbox for Reporter Gene Imaging. [PDF]

Pharmaceuticals (Basel), 2021
Stotz S, Bowden GD, Cotton JM, Pichler BJ, Maurer A.   +4 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

NOMO-1 cells expressing an NF-κB luciferase reporter gene facilitate a simple, rapid monocyte activation test that can detect a wide range of pyrogens. [PDF]

PLoS One
Nanao T, Marutani Y, Sato K, Mori T, Kitagawa T, Oku T, Nishibu T.   +6 more
europepmc   +1 more source

A reporter gene assay for determining the biological activity of therapeutic antibodies targeting TIGIT. [PDF]

Acta Pharm Sin B, 2021
Fu Z, Liu H, Wang L, Yu C, Yang Y, Feng M, Wang J.   +6 more
europepmc   +1 more source