Results 241 to 250 of about 7,567,038 (395)

DNA regions bound at low occupancy by transcription factors do not drive patterned reporter gene expression in Drosophila

Proceedings of the National Academy of Sciences of the United States of America, 2012
W. Fisher, J. Li, A. Hammonds, James B. Brown, B. Pfeiffer, Richard Weiszmann, S. MacArthur, Sean Thomas, J. Stamatoyannopoulos, M. Eisen, P. Bickel, M. Biggin, S. Celniker   +12 more
semanticscholar   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

NOMO-1 cells expressing an NF-κB luciferase reporter gene facilitate a simple, rapid monocyte activation test that can detect a wide range of pyrogens. [PDF]

PLoS One
Nanao T, Marutani Y, Sato K, Mori T, Kitagawa T, Oku T, Nishibu T.   +6 more
europepmc   +1 more source

A reporter gene assay for determining the biological activity of therapeutic antibodies targeting TIGIT. [PDF]

Acta Pharm Sin B, 2021
Fu Z, Liu H, Wang L, Yu C, Yang Y, Feng M, Wang J.   +6 more
europepmc   +1 more source

Reporter Genes

, 2017
Amer M. Najjar, Laura J. Fromme, Shahriar Yaghoubi   +2 more
openaire   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Genetically engineered secretory horseradish peroxidase is a sensitive, stable, and affordable non-lytic reporter gene system for real-time promoter activity management. [PDF]

J Biol Eng
Chang MS, Lee CY, Chang YY, Li PJ, Wu HY, Liu ES, Huang HK, Lin WW.   +7 more
europepmc   +1 more source

Evaluation of Firefly and Renilla Luciferase Inhibition in Reporter-Gene Assays: A Case of Isoflavonoids. [PDF]

Int J Mol Sci, 2021
Kenda M, Vegelj J, Herlah B, Perdih A, Mladěnka P, Sollner Dolenc M.   +5 more
europepmc   +1 more source

Gene Editing in Rat Embryonic Stem Cells to Produce In Vitro Models and In Vivo Reporters [PDF]

, 2017
Yaoyao Chen, Sonia Spitzer, Sylvia Agathou, Ragnhildur Thóra Káradóttir, Austin Smith   +4 more
openalex   +1 more source

Gene drives : Policy report

, 2016
Gene drives zijn genetische eigenschappen die zodanig in het DNA van een organisme zijn ingebouwd dat ze aan alle nakomelingen worden doorgegeven, in plaats van aan een deel. Dit werkt ook door in de volgende generaties. Vooral als organismen zich snel voortplanten, kan deze eigenschap zich snel en blijvend in een hele populatie van een organisme ...
Westra J, van der Vlugt CJB, Roesink CH, Hogervorst PAM, Glandorf DCM   +4 more
openaire   +1 more source