Results 121 to 130 of about 347,626 (258)

Reporter Gene Imaging in Therapy and Diagnosis

open access: yesTheranostics, 2012
Noninvasive molecular imaging using reporter genes is a relatively recent field in biomedical imaging that holds great promises for disease diagnosis and therapy.
Pritha Ray, Abhijit De
doaj  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Brighter reporter genes from multimerized fluorescent proteins

open access: yesBioTechniques, 2005
Guillem Genové   +2 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Construction of enterovirus G expressing reporter genes for antiviral drug screening assays. [PDF]

open access: yesBMC Vet Res
Chen K   +10 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Dual-reporter assay using two secreted luciferase genes

open access: yesBioTechniques, 2007
Chun Wu   +2 more
doaj   +1 more source

New approaches for the neuroimaging of gene expression

open access: yesFrontiers in Integrative Neuroscience, 2015
Assaf A Gilad   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy