The Role of Microsurgery and Fluorescent-reporter Genes in Establishing Mouse Models for Real-Time Imaging of Metastatic Cancer-Cell Trafficking and Colony Formation: A Revolutionary and Disruptive Technology for Metastasis Research. [PDF]
Cancer Diagn PrognMorinaga S +10 more
europepmc +1 more source
Non-invasive Reporter Gene Imaging of Cell Therapies, including T Cells and Stem Cells
, 2020 Candice Ashmore‐Harris +3 more
openalex +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Improved eukaryotic promoter-detection vector carrying two luciferase reporter genes
BioTechniques, 2003 Madhu S. Malo +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Imaging with Reporter Genes: Has Its Promise Been Delivered? [PDF]
J Nucl Med, 2019 Serganova I, Blasberg RG.
europepmc +1 more source
613. Non-Invasive Imaging of Firefly Luciferase Reporter Gene Expression Following Intramuscular Injection of Plasmid in a Mouse Model of CLI [PDF]
, 2003 openalex +1 more source