Results 21 to 30 of about 347,626 (258)

Environmental Application of Reporter-Genes Based Biosensors for Chemical Contamination Screening

open access: yesArchives of Environmental Protection, 2014
The paper presents results of research concerning possibilities of applications of reporter-genes based microorganisms, including the selective presentation of defects and advantages of different new scientific achievements of methodical solutions in ...
Matejczyk Marzena   +1 more
doaj   +1 more source

GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives

open access: yesStem Cell Reports, 2016
The ability to reliably express fluorescent reporters or other genes of interest is important for using human pluripotent stem cells (hPSCs) as a platform for investigating cell fates and gene function.
Tim Kao   +24 more
doaj   +1 more source

Abnormal dosage compensation of reporter genes driven by the Drosophila glass multiple reporter (GMR) enhancer-promoter. [PDF]

open access: yesPLoS ONE, 2011
In Drosophila melanogaster the male specific lethal (MSL) complex is required for upregulation of expression of most X-linked genes in males, thereby achieving X chromosome dosage compensation.
Corey Laverty   +3 more
doaj   +1 more source

Reporter-Expressing, Replicating-Competent Recombinant Arenaviruses

open access: yesViruses, 2016
Several arenaviruses cause hemorrhagic fever (HF) disease in humans and pose an important public health problem in their endemic regions. To date, no Food and Drug Administration (FDA)-licensed vaccines are available to combat human arenavirus infections,
Luis Martínez-Sobrido   +1 more
doaj   +1 more source

Multi-color fluorescent reporter dengue viruses with improved stability for analysis of a multi-virus infection. [PDF]

open access: yesPLoS ONE, 2018
Reporter virus is a versatile tool to visualize and to analyze virus infections. However, for flaviviruses, it is difficult to maintain the inserted reporter genes on the viral genome, limiting its use in several studies that require homogeneous virus ...
Amporn Suphatrakul   +6 more
doaj   +1 more source

Monitoring SARS-CoV-2 Infection Using a Double Reporter-Expressing Virus

open access: yesMicrobiology Spectrum, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the highly contagious agent responsible for the coronavirus disease 2019 (COVID-19) pandemic.
Kevin Chiem   +8 more
doaj   +1 more source

Imaging Molecular Pathways: Reporter Genes [PDF]

open access: yesRadiation Research, 2012
Molecular imaging is a rapidly advancing field that allows cancer biologists to look deeper into the complex inner workings of tumor cells, or whole tumors, in a non-invasive manner. In this review, we will summarize some recent advances that enable investigators to study various important biological processes in tumors in vivo.
John, Brogan   +5 more
openaire   +2 more sources

Magnetic Resonance Reporter Gene Imaging [PDF]

open access: yesTheranostics, 2012
Molecular imaging has undergone an explosive advancement in recent years, due to the tremendous research efforts made to understand and visualize biological processes. Molecular imaging by definition assesses cellular and molecular processes in living subjects, with the targets of following metabolic, genomic, and proteomic events.
Lee, Sheen-Woo   +2 more
openaire   +2 more sources

A BAC-bacterial recombination method to generate physically linked multiple gene reporter DNA constructs

open access: yesBMC Biotechnology, 2009
Background Reporter gene mice are valuable animal models for biological research providing a gene expression readout that can contribute to cellular characterization within the context of a developmental process.
Gong Shiaochin   +5 more
doaj   +1 more source

Utility of Computed Tomography Surveillance of Asymptomatic Infection in Children and Young Adults Before Allogeneic Hematopoietic Stem Cell Transplant

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Asymptomatic infection poses a significant risk for children undergoing hematopoietic stem cell transplantation (HSCT). Pre‐transplant surveillance computed tomography (CT) is commonly used to identify occult infection, though its diagnostic yield remains uncertain.
Tyler Obermark   +9 more
wiley   +1 more source

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