Results 61 to 70 of about 2,216,519 (292)

Infection by Bacterial Pathogens Expressing Type III Secretion Decreases Luciferase Activity: Ramifications for Reporter Gene Studies

open access: yesBioTechniques, 2000
Pathogenic microbes influence gene regulation in eukaryotic hosts. Reporter gene studies can define the roles of promoter regulatory sequences. The effect of pathogenic bacteria on reporter genes has not been examined.
Suzana D. Savkovic   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Orange County Reporter, April 03, 1884 [PDF]

open access: yes, 1884
Orange County Reporter newspaper from February 21, 1884 to December 25, 1884.https://stars.library.ucf.edu/cfm-orangecountyreporter/1007/thumbnail ...
Orange County Reporter
core  

Established and emerging techniques for the study of microglia: visualization, depletion, and fate mapping

open access: yesFrontiers in Cellular Neuroscience
The central nervous system (CNS) is an essential hub for neuronal communication. As a major component of the CNS, glial cells are vital in the maintenance and regulation of neuronal network dynamics.
Bianca Caroline Bobotis   +11 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Orange County Reporter, May 08, 1884 [PDF]

open access: yes, 1884
Orange County Reporter newspaper from February 21, 1884 to December 25, 1884.https://stars.library.ucf.edu/cfm-orangecountyreporter/1012/thumbnail ...
Orange County Reporter
core  

The transcriptional response of Caenorhabditis elegans to ivermectin exposure identifies novel genes involved in the response to reduced food intake [PDF]

open access: yes, 2012
We have examined the transcriptional response of Caenorhabditis elegans following exposure to the anthelmintic drug ivermectin (IVM) using whole genome microarrays and real-time QPCR.
Sai P. Ravikumar   +31 more
core   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Orange County Reporter, October 30, 1884 [PDF]

open access: yes, 1884
Orange County Reporter newspaper from February 21, 1884 to December 25, 1884.https://stars.library.ucf.edu/cfm-orangecountyreporter/1042/thumbnail ...
Orange County Reporter
core  

Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9 [PDF]

open access: yes, 2015
CRISPR/Cas9 technologies have been employed for genome editing to achieve gene knockouts and knock-ins in somatic cells. Similarly, certain endogenous genes have been tagged with fluorescent proteins. Often, the detection of tagged proteins requires high
Rojas-Fernandez, Alejandro   +5 more
core   +1 more source

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