Results 131 to 140 of about 816,185 (299)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The Effect of Guided Discovery Learning Model on Students’ Mathematical Representation Ability

open access: yes
This study aims to determine the effect of guided discovery learning model on students' mathematical representation ability. The population in this study were all VIII grade students of SMP Negeri 1 Natar even semester of the 2023/2024 academic year. The
Pramesti, Regita   +3 more
core   +1 more source

The multiple representations ability of students in linear motion

open access: yesRevista Mexicana de Física E
This research aims to reveal students’ ability to analyze the equation of position versus time, so students can describe quantities of motion with multiple representations in linear motion. Subjects included 54 students of XI grade from one of the high schools in Pasuruan and Sumenep Madura.
null Umrotul   +5 more
openaire   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

The Effect of Multi-Representation-Based Physics Learning on Students’ Representation Translation Ability in Linear Motion Topics

open access: yes
The students' disinterest and low ability to understand and translate physics concepts are challenges in physics learning. One of the solutions in this field is to implement a learning approach that can enhance students' interest and deepen their ...
Sari, Ika Mustika   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The Role of Interactive e-Modules Based on Realistic Mathematics Education to Improve Mathematical Representation Ability

open access: yes
Excellent mathematical representation ability is needed by students to develop and deepen understanding and relationships between mathematical concepts.
Annisa, Dewi   +3 more
core   +1 more source

Inquiry and Discovery Learning Model in Student's Mathematic Representation Ability

open access: yes, 2023
Representational ability is a very important ability in learning mathematics, with representational ability students can solve mathematical problems.
Putra, Imam Setiadi
core  

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