Results 151 to 160 of about 816,185 (299)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
This paper attempts to provide a synthesis and appraisal of the field of executive functions (EF). In a moment in which early education is a very important issue in Romania, the purpose of this study is to emphasize the importance of early development of
Diana ANGHEL
core
DEVELOPMENTAL STUDIES ON THE ABILITY OF TRANSFORMATIONAL REPRESENTATION
The Japanese Journal of Educational Psychology, 1987 openaire +3 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Community Media Training Organisation Audio Ability Mentoring & Training Project Cohort 2 evaluation
In 2022 the pilot Audio Ability Accessible Mentoring and Training Project (Audio Ability 1) tried a combination of mentoring and blended learning to train the first cohort of new community media makers.
Stewart, Kim +6 more
core
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Influence of Social Skills on Students\u27 Mathematical Representation Ability
Social skills play an important role in mathematics learning because they support communication, collaboration, and the presentation of ideas. At the same time, mathematical representation is a key process in expressing concepts in verbal, visual, and ...
Maula, Minhatul, Izzati, Nurma
core
Perceptual no-reference image quality assessment with meta-learning by graph representation learning and multi-scale feature fusion. [PDF]
PLoS OneJia Y, Wei L.
europepmc +1 more source