Results 91 to 100 of about 1,013,866 (199)

The liver X receptor pathway is highly upregulated in rheumatoid arthritis synovial macrophages and potentiates TLR-driven cytokine release [PDF]

, 2013
<p>Objectives: Macrophages are central to the inflammatory processes driving rheumatoid arthritis (RA) synovitis. The molecular pathways that are induced in synovial macrophages and thereby promote RA disease pathology remain poorly understood.</
Ananth, Antoniv, Asquith, Asquith, Baeten, Bresnihan, Darren Lee Asquith, Enevold, Feldmann, Fontaine, Gerlag, Haringman, He, Huang, Iain B McInnes, Iwahashi, J Alastair Gracie, Jagtar Singh Nijjar, Jahangier, James H Reilly, Janowski, Kauffmann, Kinne, Koch, Long, Lucy E Ballantine, Manhal Khuder Makdasy, Mariola Kurowska-Stolarska, Mulherin, Ospelt, Pamela B Wright, Radstake, Ridley, Sabina Patel, Sack, Sacre, Sattar, Shauna Kerr, Tamaki, van der Heijden, van Halm, van Sijl, Zhao   +42 more
core   +1 more source

Integrative electricity need prediction utilizing enhanced squeeze net and flexible Coyote optimization algorithm A combination of RCPs SSPs and socioeconomic

Scientific Reports
Rising global temperatures and frequent extreme heat waves have caused changes in people’s energy consumption patterns, leading to a significant impact on electricity consumption.
Bin Yang, Bin Song, Yadegar Abdi
doaj   +1 more source

Well-defined silica-supported olefin metathesis catalysts [PDF]

, 2009
Two triethoxysilyl-functionalized N-heterocyclic carbene ligands have been synthesized and used to prepare the corresponding second-generation ruthenium olefin metathesis catalysts.
Allen, Daryl P., Grubbs, Robert H., Van Wingerden, Matthew M.   +2 more
core   +1 more source

A Trib2-p38 axis controls myeloid leukaemia cell cycle and stress response signalling [PDF]

, 2018
Trib2 pseudokinase is involved in the etiology of a number of cancers including leukaemia, melanoma, ovarian, lung and liver cancer. Both high and low Trib2 expression levels correlate with different types of cancer.
Carmody, Ruaidhri J., Chaudhury, Shahzya, Keeshan, Karen, Magee, Aoife, Salomé, Mara, Sarrou, Evgenia, Yalla, Krishna   +6 more
core   +2 more sources

Projection of rainfall under representative concentration pathways scenarios in a data scarce region of Iraq

European Journal of Climate Change, 2020
A study has been conducted for projection of monthly rainfall in Baghdad of Iraq using a General Circulation Models (GCM) of Coupled Model Intercomparison Project Phase 5 (CMIP5) under four representative concentration pathways (RCP) scenarios namely RCP2.6, RCP4.5, RCP6.0 and RCP8.5. For this purpose, monthly gridded precipitation datasets produced by
Salman, Saleem, Houmsi, Mohamad Rajab, Ziarh, Ghaith Falah, Ismail, Tarmizi   +3 more
openaire   +3 more sources

Early retirement of power plants in climate mitigation scenarios

Environmental Research Letters, 2020
International efforts to avoid dangerous climate change aim for large and rapid reductions of fossil fuel CO _2 emissions worldwide, including nearly complete decarbonization of the electric power sector.
Robert Fofrich, Dan Tong, Katherine Calvin, Harmen Sytze De Boer, Johannes Emmerling, Oliver Fricko, Shinichiro Fujimori, Gunnar Luderer, Joeri Rogelj, Steven J Davis   +9 more
doaj   +1 more source

High glucose up-regulates ENaC and SGK1 expression in HCD-cells [PDF]

, 2006
Background/Aim: Diabetic nephropathy is associated with progressive renal damage, leading to impaired function and end-stage renal failure. Secondary hypertension stems from a deranged ability of cells within the kidney to resolve and appropriately ...
Bell LM, Bhargava A, Bland R, Christensen O, Claire Hills, Demerdash TM, Di Paolo S, Hoffman BB, Hong-Long JI, Jeanette Bennett, Khan ZA, Lang F, Lee CT, Lindschau C, Loffing J, Marshall SM, Paul Squires, Pierre Ronco, Prie D, Ricci C, Rosemary Bland, Rossier, Satlin LM, Sharma K, Symonian M, Urbach V, Waldegger S, Wang J, Weigert C, Whiteside CI, Yung S   +30 more
core   +1 more source

Projected Changes of Grassland Productivity along the Representative Concentration Pathways during 2010–2050 in China

Advances in Meteorology, 2013
The grassland is an important land use type that plays an important role in the ecosystem services supply in China. It is of great significance to the grassland management to determine the changing trend of grassland productivity and its response to ...
Feng Wu, Xiangzheng Deng, Fang Yin, Yongwei Yuan   +3 more
doaj   +1 more source

The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation. [PDF]

, 2014
BackgroundX chromosome inactivation (XCI) is a developmental program of heterochromatin formation that initiates during early female mammalian embryonic development and is maintained through a lifetime of cell divisions in somatic cells.
Bonora, Giancarlo, Minkovsky, Alissa, Patel, Sanjeet, Plath, Kathrin, Rankin-Gee, Elyse, Sahakyan, Anna   +5 more
core   +3 more sources

Future changes in seasonal-mean precipitation over West Africa under the representative concentration pathways

Nigerian Journal of Technology, 2018
This study analysed the future changes in seasonal - mean precipitation over West Africa during the mid (2040 - 2065) twenty first century using the Norwegian Earth System Model version 1 (NorESM1 - M). The NorESM1 - M has ~1.89° x 2.5° horizontal atmospheric resolution and 26 vertical levels. The skill of the model in reproducing the observed seasonal
Ekwezuo, C. S., Nnamchi, H. C., Phil-Eze, P. O.   +2 more
openaire   +3 more sources