Results 71 to 80 of about 1,013,866 (199)
Glutamate induces autophagy via the two-pore channels in neural cells [PDF]
NAADP (nicotinic acid adenine dinucleotide phosphate) has been proposed as a second messenger for glutamate in neuronal and glial cells via the activation of the lysosomal Ca2+ channels TPC1 and TPC2.
  +11 more
core +4 more sources
Climate change and excessive greenhouse gas emissions profoundly impact hydrological cycles, particularly in arid and semi-arid regions, necessitating assessments of their effects on water resource management, agriculture, soil fertility, nutrient transport, hydropower generation, and flood risk.
Pouria Nakhaei +4 more
openaire +2 more sources
Quantifying the Ancillary Benefits of the Representative Concentration Pathways on Air Quality in Europe [PDF]
This paper presents estimates of the economic benefit of air quality improvements in Europe that occur as a side effect of GHG emission reductions. We consider three climate policy scenarios that reach radiative forcing levels in 2100 of three Representative Concentration Pathways (RCPs).
Milan Ščasný +3 more
openaire +2 more sources
Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes [PDF]
Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of insulin-producing islet β cells. Biomarkers capable of identifying T1D risk and dissecting disease-related heterogeneity represent an unmet clinical need.
Evans-Molina, Carmella +4 more
core +2 more sources
Measurement(s) Land Use and Land Cover Change Technology Type(s) computational modeling technique Factor Type(s) Shared Socioeconomic Pathways scenarios • Representative Concentration Pathways scenarios • land use and land cover change Sample ...
Meng Luo +5 more
doaj +1 more source
Testosterone insulin-like effects: an in vitro study on the short-term metabolic effects of testosterone in human skeletal muscle cells [PDF]
Testosterone by promoting different metabolic pathways contributes to short-term homeostasis of skeletal muscle, the largest insulin-sensitive tissue and the primary site for insulin-stimulated glucose utilization.
Antinozzi, Cristina +8 more
core +2 more sources
To understand the mechanisms of long-term climate and carbon cycle feedback with anthropogenic impact, past simulations (1850–2005) and projection experiments (2006 to 2100) were conducted using a new Earth system model named “MIROC-ESM”, forced by four representative concentration pathway (RCP) scenarios that describe how greenhouse gases (GHGs ...
Tomohiro HAJIMA +5 more
openaire +2 more sources
Global climate targets and future consumption level: an evaluation of the required GHG intensity
Discussion and analysis on international climate policy often focuses on the rather abstract level of total national and regional greenhouse gas (GHG) emissions. At some point, however, emission reductions need to be translated to consumption level.
Bastien Girod +2 more
doaj +1 more source
Regulation of Arabidopsis 14-3-3 gene expression by GABA. [PDF]
The function in plants of the non-protein amino acid, gamma-aminobutyric acid (GABA) is poorly understood. In this study, we show that GABA down-regulates the expression of a large sub-set of 14-3-3 gene family members in Arabidopsis thaliana seedlings ...
Lancien, Muriel, Roberts, Michael R
core +1 more source
Within savanna environments, movements of elephant are influenced by changes in climate especially seasonal rainfall. In this study, we investigated the possible changes in elephant population based on projected rainfall changes using regional climate models (RCM) and Representative Concentration Pathways (RCPs).
Mildred M. Aduma +4 more
openaire +2 more sources

