Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source
Cambio, identidad y crítica: el candombe en el movimiento de la Música Popular Uruguaya
Resumen : En los años sesenta la música popular uruguaya experimenta un significativo proceso de cambio, paralelamente a la gestación y desarrollo de la dictadura cívico-militar, que se extiende hasta 1985.
Olga Picún
doaj
Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu+4 more
wiley +1 more source
Pulizia, giustizia e potere. Ruolo e significato del Terrore nell’esperienza staliniana
This articles aims to point out the close connection between public repression and hidden purges through the example of the USSR during the Stalin era. In particular, we focused on the role played by the trials have comparing and relating it with stealt ...
Filippo Ferrara ha conseguito la Laurea Triennale in Scienze della Comunicazione, indirizzo politico-istituzionale, presso l’Università degli studi di Roma Tor vergata. Attualmente è iscritto alla Laurea Magistrale in Scienze storiche dell’Università di Bologna.
doaj
The role of the regulator-gene product (repressor) in catabolite repression of β-galactosidase synthesis in Escherichia coli [PDF]
J. Palmer, V. Moses
openalex +1 more source
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
Luke A. Gilbert+12 more
semanticscholar +1 more source
A Microfluidic Multiplex Sorter for Strain Development
A new multiplex method for high‐throughput screening of yeast strains based on glucoamylase production is presented. Droplets containing single mutant yeast cells are incubated for enzyme production. A sorting platform divides mutants by their high‐ and mid‐activity levels.
Chiara Leal‐Alves+6 more
wiley +1 more source
THE CITY AND THE RESURFACING OF THE REPRESSED. SPACE IN THE NOVEL U REGISTRATURI BY ANTE KOVAČIĆ
Together with the decline of the nobility, the city schooling of a country child and the twofold village-city relationship are the key themes of Croatian realism, as well as realism world-wide.
Dejan Durić
doaj
Perceptual defense and vigilance: Prediction from the Byrne Scale of Repression-Sensitization [PDF]
L. D. Hutt, J. P. Anderson
openalex +1 more source
m6A RNA methylation promotes XIST-mediated transcriptional repression
D. P. Patil+6 more
semanticscholar +1 more source