Results 91 to 100 of about 409,457 (308)
Financial repression and economic distortions to the stage of economic growth and agricultural development in Bangladesh [PDF]
Financial repression in a developing country is not new to us.The government may take policy for financial repression due to easy collection of inflation tax to the stage of economic development.This study is concerned to find the positive relationship ...
Sikder, Md.Anowarul Islam
core
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
The role of GW182 proteins in microRNA-mediated gene silencing [PDF]
, 2013 MicroRNAs are endogenous approximately 21-nucleotide-long non-coding RNAs that act as post-transcriptional regulators of gene expression by base pairing to target mRNAs.
Mathys, Hansruedi
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Financial Repression, Bank Deposits, Real Assets and Black Money [PDF]
Consider real assets and bank deposits. If returns on deposits improve due to reduction in financial repression, then investment in real assets can fall.
Gurbachan Singh
core
The Impact of Pro-Government Militias on Human Rights Violations [PDF]
, 2014 New data show that between 1982 and 2007, in over 60 countries governments were linked to and cooperated with informal armed groups within their own borders.
Mitchell, NJ +5 more
core +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Mechanism of chromatin reassembly at the yeast PHO5 promoter upon repression [PDF]
, 2007 The goal of this study has been to elucidate the mechanisms responsible for rebuilding nucleosomes at the PHO5 promoter upon rerepression. In this work, I could unambiguously show that histones are incorporated at the PHO5 promoter upon repression ...
Schermer, Ulrike
core +1 more source