Results 81 to 90 of about 89,603 (266)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Transnational Repression: Trends, Tactics, and Policy Recommendations

open access: yes, 2023
Today, at least 38 countries employ tactics of transnational repression in as many as 91 host states. In what can be called the "toolkit" of authoritarian control, the hydra-heads of transnational repression encompass tactics ranging from surveillance to
Ozeren, Suleyman   +4 more
core  

Sobrevivir en secreto. Las conferencias comarcales y la reorganización anarquista clandestina (1874-1881)

open access: yesCahiers de Civilisation Espagnole Contemporaine, 2015
To understand Spanish anarchism in clandestinity (1874-1881) requires reexamining new pactices and organizational changes which allowed its survival.
Clara E. Lida
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

The Francoist Repression in the Catalan Countries

open access: yesCatalan Historical Review, 2008
This article offers an overview of Francoist repression in the Catalan Countries from the outbreak of the Civil War to the first decade after the establishment of the dictatorship. It covers both physical violence and measures such as economic repression,
Conxita Mir
doaj  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Rebellion, repression and welfare [PDF]

open access: yes
I develop a dynamic model of social conflict whereby manifest grievances of the poor generate the incentive of taking over political power violently. Rebellion can be an equilibrium outcome depending on the level of preexisting inequality between the ...
Juan F. Vargas
core  

Introduction: Moving Memories of Stalin-era Repression and Displacement

open access: yes, 2023
The introductory chapter situates the collection within the field of memory studies and the study of Soviet repression and its remembrance. After briefly providing the broad historical context that connects the diverse studies explored by the chapters ...
Savolainen, Ulla, Saramo, Samira
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

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