Results 101 to 110 of about 416,000 (310)
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
РОЛЬ УСНОЇ ІСТОРІЇ У РОЗКРИТТІ ІСТОРИЧНОЇ ПРАВДИ ПРО БИКІВНЮ [PDF]
Storìnki Istorìï, 2015 On the basis of eyewitness accounts of mass burials of the repressed and those executed by the NKVD of persons in Ukraine, museum exhibits and archival materials in the Memorial-Museum named after Vasyl Stus shown the importance of the oral history in ...
Д. Ю. Кравченко
doaj
Criminocorpus, 2017 The « Carte d’identité de Français » (ID card for French citizens) was enacted in France starting in October 1940. This paper examines the cooperation between the statistical service of the French finance ministry and the French interior ministry in ...
Pierre Piazza
doaj +1 more source
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao +23 more
wiley +1 more source
, 2020 The data describes global patterns of digital repression for 2019 and incorporates two composite indexes: a latent construct of digital repression, and a latent construct of digital repression capacity.
Feldstein, S (via Mendeley Data)
core +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Growth Volatility and Financial Repression: Time Series Evidence from India [PDF]
The main objective of this paper is to explore the determinants of private consumption volatility in India. While considerable effort has been expended on the examining the relationship between growth and volatility, we focus on financial repression and ...
Ang, James
core
Restorative Justice – Definition and Models [PDF]
Societas et Iurisprudentia, 2015 The study focuses on the current issues of criminal justice based primarily on the retributive justice model and presents the concept of restorative justice as an alternative which had an extensive expansion in the recent years. The first chapter briefly
Filip Vysudil
doaj