Results 61 to 70 of about 89,603 (266)

«It is necessary to bring sincere thanks to the donators who willingly responded to the call of the church to help in difficult times...»: report on activities of the Parish Council of Omsk Bogoroditze-Bratskaya Church for 1929 [PDF]

open access: yesОмский научный вестник: Серия "Общество. История. Современность", 2019
This archaeographic publication is devoted to study of history of Orthodoxy in Omsk at the late 1920s. The report on the activities of the Parish Council of Omsk Bogoroditze-Bratskaya Church for 1929 is being introduced into the scientific circulation.
A. V. Sushko
doaj   +1 more source

MYC in elongation and repression [PDF]

open access: yesNature Reviews Cancer, 2018
Transcription elongation supported by the super elongation complex, and H3K9 methylation and gene repression by G9a mediate the oncogenic function of Myc.
openaire   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

ERASE FROM THE PERSON OF THE GROUND OF PESTS AND SPIES": THE NORTH CAUCASIAN CHARACTERISTICS PROCESSES OF "BIG TERROR"

open access: yesГуманитарные и юридические исследования, 2021
The article is devoted to one of the most tragic periods in the history of our country - "great terror". The "harmful" processes of the 1930s in the North Caucasus are analyzed on the basis of their reflection in the regional press in 1937.
Elena Strekalova
doaj  

A bipartite iron-dependent transcriptional regulation of the tryptophan salvage pathway in Chlamydia trachomatis

open access: yeseLife, 2019
During infection, pathogens are starved of essential nutrients such as iron and tryptophan by host immune effectors. Without conserved global stress response regulators, how the obligate intracellular bacterium Chlamydia trachomatis arrives at a ...
Nick D Pokorzynski   +2 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

O povo e a polícia: conflitos sociais em O cortiço, de Aluísio Azevedo, e Recordações do escrivão Isaías Caminha, de Lima Barreto // The people and the police: social conflicts in O cortiço, by Aluísio Azevedo, and Recordações do escrivão Isaías Caminha, by Lima Barreto [PDF]

open access: yesSvět Literatury, 2017
The article focuses on the social conflicts depicted in two excerpts from the novels O cortiço (1890) by Aluísio Azevedo, and Recordações do escrivão Isaías Caminha (1909) by Lima Barreto.
Edu Teruki Otsuka
doaj  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Unraveling Mechanisms of Transcriptional Repression: Novel Insights from Brinker [PDF]

open access: yes, 2013
Transcriptional repressors bind cis-regulatory elements of target genes in a sequence specific manner. To antagonize transcription, repressors primarily function by recruiting accessory proteins, co-repressors, which in turn largely function by modifying
Upadhyai, Priyanka
core  

Home - About - Disclaimer - Privacy