Results 51 to 60 of about 409,457 (308)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The archives of terror and mourning in contemporary Spain

open access: yesCulture & History Digital Journal, 2014
This article takes an integral approach to the documentation generated during the Francoist dictatorship as a result of repression. It analyzes the different typologies of the archives of Spanish repression, ranging from the records and case files ...
Alfonso Manuel Villalta Luna
doaj   +1 more source

From ‘the effect of repression’ toward ‘the response to repression’ [PDF]

open access: yesCurrent Sociology, 2018
Scholars have long been interested in explaining the effect of state repression on political participation. Recent reviews of research on state repression highlighted contradictory findings about this effect, yet the core question is still debated: what accounts for the variation in the effects of repression?
openaire   +2 more sources

Conclusion: Accelerating Digital Repression and its Existential Threat to Democracy

open access: yes, 2023
This book has highlighted how the rapid expansion of new and emerging internet and communication technologies (ICTs) has significantly increased any state’s capacity for repression and social control.
Hagen, Olivia, Ogden, Chris
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Psychosocial consequences of widespread of torture and sociopolitical pressure in Iran

open access: yesSocial Medicine, 2021
Violence and political repression in general may have different psychosocial impact on societies. Studying these effects in countries with a high grade of repression based on reliable data from inside the country is difficult or even impossible, mainly ...
Siroos Mirzaei   +3 more
doaj  

Extremadura: Behind the material traces of Franco’s repression

open access: yesCulture & History Digital Journal, 2014
After the failed coup d’état of July 17th, 1936 and after the start of the Spanish Civil War that followed it, rebels carried out a repressive strategy based on the execution of thousands of people as a key tool of social control.
Laura Muñoz Encinar   +1 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Cine y guerra civil. El conflicto que no termina

open access: yesDiacronie. Studi di Storia Contemporanea, 2011
La guerra civile è stata e continua ad essere un tema di analisi, riflessione e dibattito sia in Spagna che all’estero. Sin dall’inizio della guerra, 75 anni fa, il cinema è stato usato come mezzo di propaganda.
José-Vidal Pelaz López es Profesor Titular de Historia Contemporánea en la Facultad de Filosofía y Letras de la Universidad de Valladolid. Entre sus líneas de investigación preferentes destacan la Historia de la comunicación social y la Historia política reciente. En relación a la primera podemos citar sus libros Caciques, apóstoles y periodistas. Medios de comunicación, poder y sociedad en Palencia (1898-1939) (2000) y Ver cine. Los públicos cinematográficos en el siglo XX (2002). Respecto a la segunda El Estado de las Autonomías. Nacionalismos y regionalismos en la Historia Contemporánea de España (2002), Winston Churchill. Auge y declive del Imperio británico (2003) y Castilla y León en democracia. Partidos, elecciones y personal político (1977-2007) (2007). Ha publicado también numerosos capítulos de libros y artículos en publicaciones especializadas.   +1 more
doaj  

Control and signal processing by transcriptional interference

open access: yesMolecular Systems Biology, 2009
A transcriptional activator can suppress gene expression by interfering with transcription initiated by another activator. Transcriptional interference has been increasingly recognized as a regulatory mechanism of gene expression. The signals received by
Antoine Buetti‐Dinh   +5 more
doaj   +1 more source

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