Results 211 to 220 of about 781,740 (337)

A GDF15 3' UTR variant, rs1054564, results in allele-specific translational repression of GDF15 by hsa-miR-1233-3p

, 2017
Teng, MS (Teng, Ming-Sheng), Hsu, LA (Hsu, Lung-An), Juan, SH (Juan, Shu-Hui), Lin, WC (Lin, Wen-Chi), Lee, MC (Lee, Ming-Cheng), Su, CW (Su, Cheng-Wen), Wu, S (Wu, Semon), Ko, YL (Ko, Yu-Lin)   +7 more
openalex   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Differential Roles of Two Tandem E2F Sites in Repression of the Human p107 Promoter by Retinoblastoma and p107 Proteins

, 1995
Lingyu Zhu, Lingyun Zhu, Enzhong Xie, Long‐Sheng Chang   +3 more
openalex   +2 more sources

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

Advanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan, Jiafu Li, Min Shao, Haili Bao, Ajun Geng, Jialin Yang, Yu Tao, Xinyi Chen, Tianxiong Xiao, Chunye Liu, Zhiyao Xie, Wenqian Song, Qing Cissy Yu, Hongxing Fu, Xu Han, Taochen He, Wenquan Wang, Jianfeng Chen, Sheng Yan, Shaohua Song, Liang Liu, Yi Arial Zeng   +21 more
wiley   +1 more source

Tight cooperation between Mot1p and NC2β in regulating genome-wide transcription, repression of transcription following heat shock induction and genetic interaction with SAGA

, 2011
Gianpiero Spedale, Claartje Meddens, Maria J.E. Koster, Cheuk W. Ko, Sander R. van Hooff, Frank C. P. Holstege, H. T. Marc Timmers, W.W.M. Pim Pijnappel   +7 more
openalex   +1 more source

DNA methylation inhibits p53-mediated survivin repression [PDF]

, 2009
Nancy Nabilsi, Russell R. Broaddus, David S. Loose   +2 more
openalex   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Nuclear receptor coregulator interactions: beyond the switch. [PDF]

Genes Dev
Cassim Bawa FN, Lazar MA.
europepmc   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Myeloid PDLIM2 repression as a common mechanism of infection susceptibility in lung diseases. [PDF]

Front Immunol
Gao F, Liu X, Sun F, Xiao Y, Xiao G, Qu Z.   +5 more
europepmc   +1 more source