Results 91 to 100 of about 30,544 (313)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Identification and characterization of cis-regulatory elements that target Polycomb in the mouse genome [PDF]
, 2014 Multicellular organisms consist of numerous cell types, each serving a specific function. Remarkably, almost all cells within an organism contain the same genetic information.
Jermann, Philip
core +1 more source
Reprisal Actions of Partisans in Kaunas County (1944–1952), Part 1
Genocidas ir Rezistencija, 2019 This research focuses on the punitive operations of Lithuanian partisans in Kaunas County. The data covers the voloks that belonged to Kaunas County before the administrative-territorial reform of 1946, after which the territory of the county changed ...
Gintautas Miknevičius
doaj +1 more source
A molecular switch regulating transcriptional repression and activation of PPARγ
Nature Communications, 2020 Structural studies of nuclear receptor transcription factors revealed that nearly all nuclear receptors share a conserved helix 12 dependent transcriptional activation mechanism.
Jinsai Shang +8 more
doaj +1 more source
Social and cultural activities of the university [PDF]
Sociološki Pregled, 2001 The paper deals with the meaning of university and its value (achievement of value) in a society, so, according to that, as with a specific aspect of culture.
Božović Ratko
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines [PDF]
, 2017 Polycomb repressive complex 2 (PRC2) is a histone methyltransferase that trimethylates H3K27, a mark of repressed chromatin. Mammalian PRC2 binds RNA promiscuously, with thousands of target transcripts in vivo. But what does PRC2 recognize in these RNAs?
Richard D. Paucek +17 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The Operativo Independencia in Clarín: A first experience of repressive violence mass communication
, 2018 Este trabajo tiene como objetivo estudiar las estructuras narrativas y los marcos enunciativos con los que el diario Clarín construyó una interpretación sobre la violencia represiva a lo largo de 1975, durante el primer año del llamado Operativo ...
Iturralde, Micaela, Micaela Iturralde
core +1 more source