Results 261 to 270 of about 136,304 (310)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Two ferric uptake regulator proteins in <i>Ralstonia pseudosolanacearum</i> strain OE1-1 function cooperatively in response to the extracellular iron level under ferrous iron-rich conditions. [PDF]

Appl Environ Microbiol
Tateda S, Terazawa Y, Kiba A, Ohnishi K, Hikichi Y, Tsuzuki M.   +5 more
europepmc   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

3D epigenome architecture orchestrates cis and trans regulation of flowering time in rice. [PDF]

Genome Biol
Li Y, Zhang Z, Qiu L, Zheng R, Li H, Cao Z, Guo M, Wang S, Xie L, Guan P, Huang X, Shen C, Wu H, Li W, Ouyang W, Zhang Y, Chen G, Foda M, Yan J, Wu C, Ouyang X, Li G, Xing Y, Li X.   +23 more
europepmc   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Ageing versus developmental silencing: Answers from the epigenome. [PDF]

FEBS J
Sadler KC, Storer MA, Bayin NS.
europepmc   +1 more source

The JMJD family histone demethylases: structure, mechanism of action, diseases and therapeutic targets. [PDF]

Mol Biomed
Hong Y, Guo H, Chen Q, Yu C.
europepmc   +1 more source

Influence of DNA methylation and chromatin accessibility on regulation of gene expression during <i>Trichomonas vaginalis-</i>host cell interaction. [PDF]

mBio
Muñoz D, Lizarraga A, Johnson PJ, Strobl-Mazzulla PH, de Miguel N.   +4 more
europepmc   +1 more source

Phase Separation in Chromatin Organization and Human Diseases. [PDF]

Int J Mol Sci
Zhai Z, Meng F, Kuang J, Pei D.
europepmc   +1 more source

Coclique level structure for stochastic chemical reaction networks. [PDF]

J Math Biol
Bruno S, Fu Y, Campos FA, Del Vecchio D, Williams RJ.   +4 more
europepmc   +1 more source