Results 161 to 170 of about 355,752 (283)

Isolation of super-repressor mutants in the histidine utilization system of Salmonella typhimurium [PDF]

, 1975
David C. Hagen, S L Gerson, Boris Magasanik   +2 more
openalex   +1 more source

Neuraminidase 1 Exacerbated Glycolytic Dysregulation and Cardiotoxicity by Destabilizing SIRT1 through Interactions with NRF2 and HIF1α

Advanced Science, EarlyView.
NEU1, a key regulator of glycolysis, is markedly upregulated following DOX treatment. This upregulation is attributed to HIF1α’s transcriptional repression, requiring intricate interactions with NRF2. Increased NEU1 facilitates SIRT1 lysosomal degradation, contributing to aberrant glycolytic phenotype and cardiac damage.
Ting Gao, Yufeng Tang, Tao Zeng, Jie Wang, Xiaohui Zhang, Qingbo Liu, Xun Guan, Xinyu Tang, Guangping Lu, Jiahao Li, Mingrui Liu, Dongmei Zhang, Sixuan Lv, Junlian Gu   +13 more
wiley   +1 more source

Engineering novel CRISPRi repressors for highly efficient mammalian gene regulation. [PDF]

Genome Biol
Kristof A, Karunakaran K, Allen C, Mizote P, Briggs S, Jian Z, Nash P, Blazeck J.   +7 more
europepmc   +1 more source

Binding of lactose repressor to poly d(A-T): OD and CD melting of the complex [PDF]

, 1975
Raphaèle Clement, M. Daune
openalex   +1 more source

MYC Binding Near Transcriptional End Sites Regulates Basal Gene Expression, Read‐Through Transcription, and Intragenic Contacts

Advanced Science, EarlyView.
MYC is a transcription factor (TF) that binds DNA near transcriptional start sites (TSSs) and within enhancer elements. Here, unappreciated sites of MYC binding in the vicinity of transcriptional end sites (TESs) of many genes in multiple cell types in association with numerous other TFs are described previously.
Huabo Wang, Bingwei Ma, Taylor Stevens, Jessica Knapp, Jie Lu, Edward V. Prochownik   +5 more
wiley   +1 more source

Derivatization of pBACpAK entrapment vectors for enhanced mobile genetic element transposition detection in multidrug-resistant Escherichia coli. [PDF]

Access Microbiol
Tansirichaiya S, Leartsiwawinyu W, Thanawan N, Goodman RN, Tribuddharat C, Roberts AP.   +5 more
europepmc   +1 more source

Proteolytic cleavage of bacteriophage lambda repressor in induction.

, 1975
Jeffrey W. Roberts, Charles W.M. Roberts
openalex   +1 more source

Derepression of Uridine Diphosphate-Glucose Pyrophosphorylase ( galU ) in capR ( lon ), capS , and capT Mutants and Studies on the galU Repressor [PDF]

, 1973
C E Buchanan, Alvin Markovitz
openalex   +1 more source

An Antagonism Between Ethylene Signaling and DNA Methylation Orchestrates the Progression of Leaf Senescence in Non‐heading Chinese Cabbage

Advanced Science, EarlyView.
CMT2 mediates the maintenance of DNA methylation on the promoters of SAGs, thereby inhibiting EIN3A untimely activating SAGs’ expression. Aging‐impelled striking upregulation of EIN3A strongly suppresses the expression of CMT2 to reduce the methylation level, which releases the activation of EIN3A on SAGs, thus initiating and accelerating the ...
Dingyu Zhang, Yong Luo, Han Wang, Xiaofeng Li, Liming Miao, Lu Gao, Haibo Hao, Xinman Wang, Benke Kuai, Hongfang Zhu, Guodong Ren   +10 more
wiley   +1 more source

Genome-Wide Identification of <i>GmARF9b</i>/<i>GmARF2a</i> Negatively Regulate Root Growth in Soybean. [PDF]

Int J Mol Sci
Li D, Miao T, Liao H, Zhong Y.
europepmc   +1 more source