Results 161 to 170 of about 334,121 (353)
Transcription factor clusters regulate genes in eukaryotic cells [PDF]
Transcription is regulated through binding factors to gene promoters to activate or repress expression, however, the mechanisms by which factors find targets remain unclear. Using single-molecule fluorescence microscopy, we determined in vivo stoichiometry and spatiotemporal dynamics of a GFP tagged repressor, Mig1, from a paradigm signaling pathway of
arxiv
Interactions between de-repressed F-like R factors and wild type Colicin B factors: superinfection immunity and represser susceptibility [PDF]
Anna Frydman, Elinor Meynell
openalex +1 more source
Roles of Kdm6a and Kdm6b in Regulation of Mammalian Neural Regeneration
This study reveals that Kdm6a plays key roles in repressing either peripheral nervous system (PNS) or central nervous system (CNS) axon regeneration, whereas Kdm6b is not involved in regulating CNS axon regeneration. Moreover, both demethylases are able to regulate CNS neuronal survival after injury, but with non‐overlapping mechanisms.
Shu‐Guang Yang+13 more
wiley +1 more source
Chromatin Organization Governs Transcriptional Response and Plasticity of Cancer Stem Cells
Through a combination of transcriptomic and histone mapping studies integrated with chromatin imaging, we define how chromatin organization in nanoscale packing domains fine tunes the plasticity of cancer stem cells (CSCs) driving evasion from and survival after chemotherapy.
Yinu Wang+20 more
wiley +1 more source
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu+13 more
wiley +1 more source
Mutations Affecting the Repressibility of Arginine Biosynthetic Enzymes in Sacchromyces cerevisiae [PDF]
J. Béchet, Marcelle Grenson, J.M. Wiame
openalex +1 more source
Shrimp Virus Regulates ROS Dynamics via the Nrf2 Pathway to Facilitate Viral Replication
Viruses manipulate host ROS as a strategy to achieve successful infection. WSSV exploits Nrf2 pathway to maintain ROS homeostasis and establishes a positive feedback loop to facilitate WSSV replication. Wsv220 competitively binds to Keap1 to activate Nrf2. Nrf2 up‐regulates LvG6PDH to produce more NADPH and GSH to eliminate excessive ROS.
Honghui He+6 more
wiley +1 more source
Interactions between DNA-bound repressors govern regulation by the λ phage repressor [PDF]
Alexander D. Johnson+2 more
openalex +1 more source