Results 291 to 300 of about 334,121 (353)

Regulatory interplay between SR proteins governs CLK1 kinase splice variants production. [PDF]

RNA
Shkreta L, Delannoy A, Toutant J, Chabot B.   +3 more
europepmc   +1 more source

Dynamic filtering by two-dimensional 1H NMR with application to phage lambda repressor.

, 1984
Michael A. Weiss, J L Eliason, David J. States   +2 more
openalex   +1 more source

Manipulating the Light Systemic Signal HY5 Greatly Improve Fruit Quality in Tomato

Advanced Science, EarlyView.
This study establishes that HY5, activated by low‐dose light, acts as a systemic signal to enhance tomato fruit quality by directly promoting carotenoid synthesis and sugar metabolism. These findings demonstrate HY5's mobility from leaves to fruits and its application potential through nighttime LED lighting, offering a practical strategy for crop ...
Jiachun Wang, Xiaomeng Li, Jiajia Li, Han Dong, Zhangjian Hu, Xiaojian Xia, Jingquan Yu, Yanhong Zhou   +7 more
wiley   +1 more source

Relationship between androgen receptor and androgen receptor-related protein expression in breast cancers focusing on morphologically identified carcinoma with apocrine differentiation. [PDF]

Sci Rep
Nishida H, Kato A, Kaimori R, Kawamura K, Daa T.   +4 more
europepmc   +1 more source

Cloning and characterization of the repressor gene of the Staphylococcus aureus lactose operon

, 1987
Babak Oskouian, George C. Stewart
openalex   +1 more source

Engineered Genetic Circuits Activated by Bezafibrate Improve ESC‐Based TAA Cancer Vaccine Efficacy and PD‐L1 Nanobody Therapy

Advanced Science, EarlyView.
Synthetic gene circuits regulated by bezafibrate are developed to express tumor antigens and PD‐L1 nanobody (PD‐L1nb), enhancing cancer immunotherapy. Delivered via HEK293T cells, ESCs, or directly injected the plasmids containing the circuit into the tumor, the circuits reduce tumor growth, boost CD8+ T cells, and minimize T cell exhaustion.
Meiling Jin, Shuzhen Liu, Mingshuo Zhan, Jian‐Dong Huang   +3 more
wiley   +1 more source

An Overview of Lsr2 Repressor Effect in Streptomyces spp. Secondary Metabolism. [PDF]

Microorganisms
Cuervo L, Malmierca MG, Olano C.
europepmc   +1 more source

STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy

Advanced Science, EarlyView.
STING agonists show promise in preclinical studies in boosting an anti‐tumor response using the immune system. However, different limitations remain, and future research is needed to better understand how STING activation impacts the tumor microenvironment, identify effective combination strategies, and determine the best tumor types for STING agonist ...
Laura Gehrcken, Christophe Deben, Evelien Smits, Jonas R.M. Van Audenaerde   +3 more
wiley   +1 more source

Autocrine GDF10 Inhibits Hepatic Stellate Cell Activation via BMPR2/ALK3 Receptor to Prevent Liver Fibrosis

Advanced Science, EarlyView.
Liver fibrosis is a growing global health burden with no specific treatment. HSC activation is the predominant driver of liver fibrogenesis and the current focus in antifibrotic drug discovery. This study identifies autocrine GDF10 activates BMPR2/ALK3‐SMAD1/5/8‐SMAD7 pathway to counteract the TGF‐β‐SMAD2/3 pathway in HSCs, thereby inhibiting HSC ...
Yinliang Zhang, Xiaochen Gai, Yuhui Li, Zuoyu Chen, Xi Zhang, Wei Qiao, Ping Qiu, Chunyuan Du, Sufang Sheng, Jingran Hao, Yujie Zhang, Heng Fan, Xiaorong Li, Ming Liu, Jun Zhang, Zhe Pan, Yongsheng Chang   +16 more
wiley   +1 more source

Regulation of <i>P _suc</i> , a sucrose-inducible promoter in <i>Caulobacter crescentus</i>. [PDF]

MicroPubl Biol
NewRingeisen E, Jordahl J, Bowers L.
europepmc   +1 more source