Results 341 to 350 of about 491,654 (394)

Crystallization of the Arc repressor

Journal of Molecular Biology, 1985
Arc, a repressor from Salmonella phage P22 has been crystallized from ammonium phosphate at pH 8.0. The crystals form in space group P212121 with a = 90.26 A, b = 52.88 A and c = 47.58 A. The crystals diffract to 2.2 A resolution.
S R, Jordan, C O, Pabo, A K, Vershon, R T, Sauer   +3 more
openaire   +2 more sources

Repressors of healthy ageing

Nature Reviews Genetics, 2020
RNA interference screening in Caenorhabditis elegans has identified two repressive epigenetic regulators of age-related behavioural performance that are conserved in mammals.
openaire   +2 more sources

Interaction of effecting ligands with lac repressor and repressor-operator complex

Biochemistry, 1975
The equilibrium association constants for the binding of a wide variety of effecting ligands of the lac repressor were measured by equilibrium dialysis. Also, detailed investigations of the apparent rate of dissociation of repressor-operator comples as a function of ligand concentration were carried out for several inducers and anti-inducers.
M D, Barkley, A D, Riggs, A, Jobe, S, Burgeois   +3 more
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Construction of A Dimeric Repressor: Dissection of Subunit Interfaces in Lac Repressor

Biochemistry, 1994
Formation of the lactose repressor tetramer is postulated to involve two subunit interfaces, one primarily contributing to monomer-monomer assembly to dimer and the second to dimer-dimer association to tetramer. The latter interface requires a heptad repeat of three leucines at the C-terminus of lac repressor that is presumed to form an abbreviated ...
J, Chen, R, Surendran, J C, Lee, K S, Matthews   +3 more
openaire   +2 more sources

The Whole Lactose Repressor

Science, 1996
The lactose repressor turns the bacterial genes for lactose metabolism on and off. This system has served as a blueprint for the study of both eukaryotic and prokaryotic gene regulation for decades. In this issue of Science , the crystal structure of the whole lactose repressor in a complex with DNA and its inducer ...
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lac repressor-operator interaction. Analysis of the X86 repressor mutant

Journal of Molecular Biology, 1976
Abstract In vitro measurements show that the X86 repressor, which has an increased affinity for the lac operator as compared to wild-type repressor, also has an increased affinity for non-operator sites on Escherichia coli DNA. The rate constant of association of repressor and operator is decreased by E.
openaire   +2 more sources

The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells

Nature Cell Biology, 2000
E. Batlle, E. Sancho, C. Francı́, David Domı́nguez, M. Monfar, J. Baulida, A. G. Herreros   +6 more
semanticscholar   +1 more source

Genetic Repressors

Scientific American, 1970
M, Ptashne, W, Gilbert
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Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

Nature, 1995
A. Hörlein, A. Näär, T. Heinzel, J. Torchia, B. Gloss, R. Kurokawa, A. Ryan, Yasutomi Kamei, M. Söderström, C. Glass, M. Rosenfeld   +10 more
semanticscholar   +1 more source

Repressors

1976
S, Bourgeois, M, Pfahl
openaire   +2 more sources