Results 101 to 110 of about 2,089,944 (391)
The fundamental principles of reproducibility [PDF]
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2021 Reproducibility is a confused terminology. In this paper, I take a fundamental view on reproducibility rooted in the scientific method. The scientific method is analysed and characterized in order to develop the terminology required to define reproducibility.
openaire +4 more sources
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
The Reproducibility of Lists of Differentially Expressed Genes in Microarray Studies [PDF]
, 2007 Reproducibility is a fundamental requirement in scientific experiments and clinical contexts. Recent publications raise concerns about the reliability of microarray technology because of the apparent lack of agreement between lists of differentially ...
Brett Thorn +49 more
core +2 more sources
Reporting Guidelines to Increase the Reproducibility and Comparability of Research on Microplastics
Applied Spectroscopy, 2020 The ubiquitous pollution of the environment with microplastics, a diverse suite of contaminants, is of growing concern for science and currently receives considerable public, political, and academic attention. The potential impact of microplastics in the
Win Colton Cowger +22 more
semanticscholar +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Frontiers in Behavioral Neuroscience, 2017 Mice produce ultrasonic vocalizations (USVs) in a variety of social situations, and USVs have been leveraged to study many neurological diseases including verbal dyspraxia, depression, autism and stuttering.
Terra D. Barnes +3 more
doaj +1 more source
Inflammatory and angiogenic protein detection in the human vitreous : cytometric bead assay [PDF]
, 2011 Introduction. To evaluate clinical feasibility and reproducibility of cytometric bead assay (CBA) in nondiluted vitreous samples of patients with age-related macular degeneration (ARMD), diabetic macular edema (DME), and central retinal vein occlusion ...
Koch, Frank H. +2 more
core
In the name of reproducibility [PDF]
Lab Animal, 2018 Adhering to mouse nomenclature guidelines ensures that research is discoverable, replicable, and less wasteful. So why don’t researchers do it?
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
A Collaborative Approach to Computational Reproducibility [PDF]
, 2016 Although a standard in natural science, reproducibility has been only episodically applied in experimental computer science. Scientific papers often present a large number of tables, plots and pictures that summarize the obtained results, but then ...
Capone, Rebecca +4 more
core +4 more sources