Results 101 to 110 of about 1,534,989 (367)

This Poster is Reproducible

, 2019
This paper describes the process of making the 'What Does a University Look Like?' poster for the 2019 VIVO conference.It Demonstrates workflows between Dimensions, Gigantum, Fighsare, and ...
Porter, Simon, Watts, Jared
openaire   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Synthesis of Novel CuO Nanosheets and Their Non-Enzymatic Glucose Sensing Applications

Sensors, 2013
In this study, we have developed a sensitive and selective glucose sensor using novel CuO nanosheets which were grown on a gold coated glass substrate by a low temperature growth method.
Magnus Willander, Xianjie Liu, Valerio Beni, Zafar Hussain Ibupoto, Kimleang Khun   +4 more
doaj   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

A community-maintained standard library of population genetic models

eLife, 2020
The explosion in population genomic data demands ever more complex modes of analysis, and increasingly, these analyses depend on sophisticated simulations.
Jeffrey R Adrion, Christopher B Cole, Noah Dukler, Jared G Galloway, Ariella L Gladstein, Graham Gower, Christopher C Kyriazis, Aaron P Ragsdale, Georgia Tsambos, Franz Baumdicker, Jedidiah Carlson, Reed A Cartwright, Arun Durvasula, Ilan Gronau, Bernard Y Kim, Patrick McKenzie, Philipp W Messer, Ekaterina Noskova, Diego Ortega-Del Vecchyo, Fernando Racimo, Travis J Struck, Simon Gravel, Ryan N Gutenkunst, Kirk E Lohmueller, Peter L Ralph, Daniel R Schrider, Adam Siepel, Jerome Kelleher, Andrew D Kern   +28 more
doaj   +1 more source

The Economics of Reproducibility in Preclinical Research

PLoS Biology, 2015
Low reproducibility rates within life science research undermine cumulative knowledge production and contribute to both delays and costs of therapeutic drug development.
L. Freedman, I. Cockburn, Timothy S. Simcoe   +2 more
semanticscholar   +1 more source

Reproducibility of EEG functional connectivity in Alzheimer’s disease

Alzheimer's Research & Therapy, 2020
Background Although numerous electroencephalogram (EEG) studies have described differences in functional connectivity in Alzheimer’s disease (AD) compared to healthy subjects, there is no general consensus on the methodology of estimating functional ...
Casper T. Briels, D. Schoonhoven, C. Stam, H. de Waal, P. Scheltens, A. Gouw   +5 more
semanticscholar   +1 more source

Reproducibility for Everyone - Introduction to Reproducibility

, 2019
This presentation forms part of a eight-series presentation set covering various aspects of reproducibility. The presentation was developed by Reproducibility for Everyone. For more information visit their website - http://www.repro4everyone.org.The Introduction to Reproducibility provide context and motivation for caring about reproducibility in ...
Abitua, Angela, Clyburne-Sherin, April, Schwessinger, Benjamin, Alicea, Bradly, Ganguly, Diep, Kamens, Joanne, Teytelman, Lenny, Schmelling, Nicolas, Roy, Sonali, Weissgerber, Tracey L.   +9 more
openaire   +1 more source

WalT: A reproducible testbed for reproducible network experiments [PDF]

2016 IEEE Conference on Computer Communications Workshops (INFOCOM WKSHPS), 2016
Testing wireless networks is a challenging task, so many research papers limit their evaluation section to simulation. At the same time, several large-scale publicly shared testbeds such as ORBIT, w-iLab.t, or IoT-LAB propose valuable means for validating new protocols.
Brunisholz, Pierre, Duble, Etienne, Rousseau, Franck, Duda, Andrzej   +3 more
openaire   +2 more sources

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source