Results 91 to 100 of about 978,638 (304)
Investigating Reproducibility Challenges in LLM Bugfixing on the HumanEvalFix Benchmark
SoftwareBenchmark results for large language models often show inconsistencies across different studies. This paper investigates the challenges of reproducing these results in automatic bugfixing using LLMs, on the HumanEvalFix benchmark.
Balázs Szalontai +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Grand Rounds: Research Reproducibility - Brian Sauer PhD, MS (02-06-2018)
, 2018 "Spencer S. Eccles Health Sciences Library Grand Rounds: Research Reproducibility (GRRR). "Workflow Management and Research Reproducibility" presented by Brian C. Sauer, PhD, MS.
Brian Sauer, PhD, MS
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Reproducibility of neuroimaging analyses across operating systems
Frontiers in Neuroinformatics, 2015 Neuroimaging pipelines are known to generate different results depending on the computing platform where they are compiled and executed. We quantify these differences for brain tissue classification, fMRI analysis, and cortical thickness (CT) extraction,
Tristan eGlatard +12 more
doaj +1 more source
Reproducibility in research [PDF]
Disease Models & Mechanisms, 2011 Summary Progress in biomedical research depends in part on being able to build on the findings of other researchers – and thereby on being able to apply others’ methods to your own research. However, most of us have struggled to understand how to repeat or adapt another researcher’s study because of minimal or missing details in the ...
openaire +3 more sources
Grand Rounds: Research Reproducibility - Bryan W. Jones (01-09-2018)
, 2018 Spencer S. Eccles Health Sciences Library Grand Rounds: Research Reproducibility (GRRR). "Digital Imaging and Peer Review: What is Allowed? What is Not Allowed? What is Fake?" presented by Bryan W. Jones.
Bryan W. Jones
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
BiomedicinesThe development of bacteriophages (phages) as active pharmaceutical ingredients for the treatment of patients is on its way and regulatory agencies are calling for reliable methods to assess phage potency.
Nicolas Dufour +2 more
doaj +1 more source