Results 111 to 120 of about 978,638 (304)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
AlgorithmsThis study presents the first quantitative meta-analysis in cooperative multi-agent reinforcement learning (MARL). Undertaken on the StarCraft Multi-Agent Challenge (SMAC) benchmark, we quantify reproducibility and statistical heterogeneity across ...
Rex Li, Chunyu Liu
doaj +1 more source
Grand Rounds: Research Reproducibility - Derek Warner (04-10-2018)
, 2018 Spencer S. Eccles Health Sciences Library Grand Rounds: Research Reproducibility (GRRR). "Knowing Your Human Cell Line is What You Think it is" by Derek Warner, Research Associate, DNA Sequencing Facility.
Derek Warner
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
No Reproducibility, No Progress: Rethinking CT Benchmarking
Journal of ImagingReproducibility is a cornerstone of scientific progress, yet in X-ray computed tomography (CT) reconstruction, it remains a critical and unresolved challenge. Current benchmarking practices in CT are hampered by the scarcity of openly available datasets,
Dmitry Polevoy +3 more
doaj +1 more source
Ophthalmic Research, 2009 A combination of a single drop of each of 0.5% tropicamide and of 10% phenylephrine hydrochloride instilled after routine applanation tonometry gave consistent pupil dilatation in a population with cataract studied over 5 years. The dilatation allows reproducible photographic documentation of cataracts in long-term studies.
openaire +2 more sources
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Clinical & Translational ImmunologyObjectives Amino acid variations across more than 30 immunoglobulin (Ig) allotypes may introduce structural changes that influence recognition by anti‐Ig detection reagents, consequently confounding interpretation of antibody responses, particularly in ...
Ruth A Purcell +15 more
doaj +1 more source
A Fair Comparison in Deep Learning-Based QSM Reconstruction
IEEE AccessIn medical imaging, deep learning has greatly enhanced image quality, however, issues on the generalization of network performance for datasets of untrained characteristics (i.e., out-of-distribution data) have risen.
Chungseok Oh +4 more
doaj +1 more source
Grand Rounds Research Reproducibility - Matt Haber, PhD (03-27-2018)
, 2018 Spencer S. Eccles Health Sciences Library Grand Rounds: Research Reproducibility (GRRR). "Positively Misleading Errors" presented by Matt Haber, PhD, Chair Department Of Philosophy and Center for Quantitative Biology, University of Utah. GRRR is a weekly
Matt Haber, PhD
core