Results 151 to 160 of about 2,065,577 (395)
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
Leakage and the reproducibility crisis in machine-learning-based science
Patterns, 2023 Sayash Kapoor, Arvind Narayanan
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang +10 more
wiley +1 more source
HiCRep: assessing the reproducibility of Hi-C data using a stratum-adjusted correlation coefficient
bioRxiv, 2017 Hi-C is a powerful technology for studying genome-wide chromatin interactions. However, current methods for assessing Hi-C data reproducibility can produce misleading results because they ignore spatial features in Hi-C data, such as domain structure and
Tao Yang +6 more
semanticscholar +1 more source
Reproducibility Report for "Learning To Count Objects In Natural Images For Visual Question Answering" [PDF]
arXiv, 2018 This is the reproducibility report for the paper "Learning To Count Objects In Natural Images For Visual QuestionAnswering"
arxiv
Interactive Tools for Reproducible Science -- Understanding, Supporting, and Motivating Reproducible Science Practices [PDF]
arXiv, 2020 Reproducibility should be a cornerstone of science as it enables validation and reuse. In recent years, the scientific community and the general public became increasingly aware of the reproducibility crisis, i.e. the wide-spread inability of researchers to reproduce published work, including their own.
arxiv
Progress on reproducibility [PDF]
Science, 2018 Ideas supported by well-defined and clearly described methods and evidence are one of the cornerstones of science. After several publications indicated that a substantial number of scientific reports may not be readily reproducible, the scientific community and public began engaging in discussions about mechanisms to measure and enhance the ...
openaire +3 more sources
Acute post-exercise cardiovascular responses in healthy participants [PDF]
The overall aim of this project was to investigate the acute cardiovascular post-exercise response in healthy individuals. The aim of the first study was to establish the within day and between day reproducibility of supine and tilt baroreflex ...
Reynolds, Linda J
core
Molecular Oncology, EarlyView.Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad +13 more
wiley +1 more source
Integration of “omics” Data and Phenotypic Data Within a Unified Extensible Multimodal Framework
Frontiers in Neuroinformatics, 2018 Analysis of “omics” data is often a long and segmented process, encompassing multiple stages from initial data collection to processing, quality control and visualization. The cross-modal nature of recent genomic analyses renders this process challenging
Samir Das +35 more
doaj +1 more source