Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Ethological Constraints and Welfare-Related Bias in Laboratory Mice: Implications of Housing, Lighting, and Social Environment. [PDF]
Török HK, Bárdos B.
europepmc +1 more source
TannyNipa/SVRRC-DNA-Clustering: SVRRC-DNA-Clustering v1.1 — IEEE Access Reproducibility Package
TannyNipa
openalex +1 more source
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
Genomic selection and reproducibility: are complex models distracting us from true scientific validity in the presence of genotype-by-environment interaction? [PDF]
Howard R, Lipka AE.
europepmc +1 more source
Assessment of metabolite quantitation reproducibility in serial 1H-MR spectroscopic imaging of human brain using a stereotactic immobilization/repositioning frame [PDF]
A.Z. Damyanovich +2 more
openalex +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Evaluating the Performance of AI Large Language Models in Detecting Pediatric Medication Errors Across Languages: A Comparative Study. [PDF]
Abu-Farha RK +5 more
europepmc +1 more source

