Results 51 to 60 of about 2,065,577 (395)

Reproducibility in density functional theory calculations of solids

open access: yesScience, 2016
A comparison of DFT methods Density functional theory (DFT) is now routinely used for simulating material properties. Many software packages are available, which makes it challenging to know which are the best to use for a specific calculation ...
K. Lejaeghere   +68 more
semanticscholar   +1 more source

Addressing variability in iPSC-derived models of human disease: guidelines to promote reproducibility

open access: yesDisease Models & Mechanisms, 2020
Induced pluripotent stem cell (iPSC) technologies have provided in vitro models of inaccessible human cell types, yielding new insights into disease mechanisms especially for neurological disorders.
Viola Volpato, C. Webber
semanticscholar   +1 more source

Registered report: Intestinal inflammation targets cancer-inducing activity of the microbiota

open access: yeseLife, 2015
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
Kate Eaton   +2 more
doaj   +1 more source

Challenges to the Reproducibility of Machine Learning Models in Health Care.

open access: yesJournal of the American Medical Association (JAMA), 2020
Reproducibility has been an important and intensely debated topic in science and medicine for the past few decades.1 As the scientific enterprise has grown in scope and complexity, concerns regarding how well new findings can be reproduced and validated ...
Andrew Beam, A. Manrai, M. Ghassemi
semanticscholar   +1 more source

Replication Study: The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

open access: yeseLife, 2017
In 2015, as part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Chroscinski et al., 2015) that described how we intended to replicate selected experiments from the paper “The CD47-signal regulatory protein alpha (SIRPa)
Stephen K Horrigan   +1 more
doaj   +1 more source

Artificial intelligence faces reproducibility crisis.

open access: yesScience, 2018
The booming field of artificial intelligence (AI) is grappling with a replication crisis, much like the ones that have afflicted psychology, medicine, and other fields over the past decade.
M. Hutson
semanticscholar   +1 more source

Unified Behavioral Scoring for Preclinical Models

open access: yesFrontiers in Neuroscience, 2020
Preclinical mental health research relies upon animal models, and whilst many encouraging advances are being made, reproducibility and translational relevance may be limited by sub-optimal testing or model choices.
David J. Harrison   +7 more
doaj   +1 more source

Laying foundations to quantify the "Effort of Reproducibility" [PDF]

open access: yesarXiv, 2023
Why are some research studies easy to reproduce while others are difficult? Casting doubt on the accuracy of scientific work is not fruitful, especially when an individual researcher cannot reproduce the claims made in the paper. There could be many subjective reasons behind the inability to reproduce a scientific paper.
arxiv  

Helvacioglu reproducibility index:a new algorithm to evaluate the effects of misalignments on the measurements of retinal nerve fiber layer by spectral-domain OCT [PDF]

open access: yesInternational Journal of Ophthalmology, 2015
AIM:To evaluate the effect of misalignment on the measurements of retinal nerve fiber layer (RNFL) by spectral-domain optical coherence tomography (OCT).METHODS:A total of 42 eyes from 21 healthy young subjects underwent RNFL measurements with RTVue ...
Firat Helvacioglu   +4 more
doaj   +1 more source

Measuring reproducibility of high-throughput experiments

open access: yes, 2011
Reproducibility is essential to reliable scientific discovery in high-throughput experiments. In this work we propose a unified approach to measure the reproducibility of findings identified from replicate experiments and identify putative discoveries ...
Bickel, Peter J.   +3 more
core   +1 more source

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