Results 91 to 100 of about 630,563 (312)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Reproducibility of the point connection technique for measuring hallux valgus angles using a smartphone application

Journal of the Foot & Ankle, 2022
Objective: A) To evaluate the reliability of a new technique for the measurement of both intermetatarsal and hallux valgus angles. B) To evaluate whether this technique can be performed with the aid of a smartphone application.
Luis Felipe Cortês Padilha, Thomás Almeida de Sousa Nogueira , Bruno Povoleri Marano, Rodrigo Monteiro Camisão, João Victor Costa Barreto Brígido, Vitor Almeida Ribeiro de Miranda   +5 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Results of the ISMRM 2020 joint Reproducible Research & Quantitative MR study groups reproducibility challenge on phantom and human brain T₁ mapping

, 2023
Mathieu Boudreau, Agâh Karakuzu, Julien Cohen‐Adad, Ecem Bozkurt, Madeline Carr, Marco Castellaro, Luis Concha, Mariya Doneva, Seraina A. Dual, Alex Ensworth, Alexandru Foias, Véronique Fortier, Refaat E. Gabr, Guillaume Gilbert, Carri Glide‐Hurst, Matthew Grech‐Sollars, Siyuan Hu, Oscar Jalnefjord, Jorge Jovicich, Kübra Keskin, Peter Koken, Anastasia Kolokotronis, Simran Kukran, Nam G. Lee, Ives R. Levesque, Bochao Li, Dan Ma, Burkhard Mädler, Nyasha G. Maforo, Jamie Near, Erick H. Pasaye, Alonso Ramírez-Manzanares, Ben Statton, Christian Stehning, Stefano Tambalo, Ye Tian, Chenyang Wang, Kilian Weis, Niloufar Zakariaei, Shuo Zhang, Ziwei Zhao, Nikola Stikov   +41 more
openalex   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Intra-rater and Inter-instrument Reliability on Range of Movement of Active Knee Extension

Motriz: Revista de Educacao Fisica
The objective of the present study was to evaluate the reliability of intra-rater and inter-instrument measures during two flexibility programs. Fifty-three active and healthy males, aged between 18 and 28 years old, were randomly included in three ...
Germanna de Medeiros Barbosa, Glauko André de Figueirêdo Dantas, Bianca Rodrigues da Silva, Scheila Marisa Pinheiro, Heleodório Honorato dos Santos, Wouber Hérickson de Brito Vieira   +5 more
doaj   +1 more source

Robust Monte-Carlo Simulations in Diffusion-MRI: Effect of the Substrate Complexity and Parameter Choice on the Reproducibility of Results. [PDF]

Front Neuroinform, 2020
Rafael-Patino J, Romascano D, Ramirez-Manzanares A, Canales-Rodríguez EJ, Girard G, Thiran JP.   +5 more
europepmc   +1 more source

Electrogastrographic Norms in Children: Toward the Development of Standard Methods, Reproducible Results, and Reliable Normative Data [PDF]

, 2001
Joseph Levy, Jennifer Harris, Jiande Chen, Dan Sapoznikov, Benita Riley, Wendy De La Nuez, Anna Khaskelberg   +6 more
openalex   +1 more source

Data and program codes to reproduce the results of seismic tomography for Okmok

, 2022
Ekaterina Kasatkina, Iván Koulakov
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source