Results 91 to 100 of about 1,117,074 (345)

Near-optimal RNA-Seq quantification [PDF]

, 2015
We present a novel approach to RNA-Seq quantification that is near optimal in speed and accuracy. Software implementing the approach, called kallisto, can be used to analyze 30 million unaligned paired-end RNA-Seq reads in less than 5 minutes on a ...
Bray, Nicolas, Melsted, Páll, Pachter, Lior, Pimentel, Harold   +3 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Comparison of the Reproducibility of Various Tooth Color Measurement Techniques

Journal of Dental School
Objective(s): Accurate shade selection is the most challenging step in the natural reconstruction of teeth in most cases. The most commonly used method for adapting the color of tooth and restorative materials is the visual matching of the tooth color ...
Marzieh Rohaninasab, Hamed Bahrami Maleki, Nastaran Dabiri Shahabi, Sadra Ahmady   +3 more
doaj   +1 more source

Data Sharing and Reproducibility of Results-Does It Matter for HIV Nursing? [PDF]

J Assoc Nurses AIDS Care, 2021
Relf MV, Overstreet K.
europepmc   +1 more source

An investigation into the feasibility of myoglobin-based single-electron transistors

, 2012
Myoglobin single-electron transistors were investigated using nanometer- gap platinum electrodes fabricated by electromigration at cryogenic temperatures. Apomyoglobin (myoglobin without heme group) was used as a reference.
Bendall D S, David Lederman, Debin Li, Dong J, Garrett R H, Hayashi T, Li D, Park J, Peter M Gannett, Spiro T G   +9 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Adaptação transcultural, confiabilidade e validade da escala de resiliência

Cadernos de Saúde Pública
Busca-se apresentar os resultados da adaptação transcultural para o português da escala de resilência de Wagnild & Young e da avaliação psicométrica desta.
Renata P. Pesce, Simone G. Assis, Joviana Q. Avanci, Nilton C. Santos, Juaci V. Malaquias, Raquel Carvalhaes   +5 more
doaj  

Hearing screening using the uHear™ smartphone-based app: reproducibility of results from two response modes. [PDF]

Codas, 2023
Cunha MLSD, Lopes MDS, Meira TC, Corona AP.   +3 more
europepmc   +1 more source

BEAT: An Open-Source Web-Based Open-Science Platform [PDF]

, 2017
With the increased interest in computational sciences, machine learning (ML), pattern recognition (PR) and big data, governmental agencies, academia and manufacturers are overwhelmed by the constant influx of new algorithms and techniques promising ...
Anjos, André, El-Shafey, Laurent, Marcel, Sébastien   +2 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source