Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Reproducibility, reliability and validity of measurements obtained from Cecile3 digital models
Brazilian Oral Research, 2009 The aim of this study was to determine the reproducibility, reliability and validity of measurements in digital models compared to plaster models. Fifteen pairs of plaster models were obtained from orthodontic patients with permanent dentition before ...
Gustavo Adolfo Watanabe-Kanno +4 more
doaj +1 more source
An investigation into the feasibility of myoglobin-based single-electron transistors
, 2012 Myoglobin single-electron transistors were investigated using nanometer- gap platinum electrodes fabricated by electromigration at cryogenic temperatures. Apomyoglobin (myoglobin without heme group) was used as a reference.
Bendall D S +9 more
core +1 more source
The Reproducibility of Lists of Differentially Expressed Genes in Microarray Studies [PDF]
, 2007 Reproducibility is a fundamental requirement in scientific experiments and clinical contexts. Recent publications raise concerns about the reliability of microarray technology because of the apparent lack of agreement between lists of differentially ...
Brett Thorn +49 more
core +2 more sources
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
RELIABILITY OF A NEW BAROPODOMETRY PLATFORM DURING BAREFOOT WALKING IN HEALTHY ADULTS [PDF]
Acta Ortopédica BrasileiraObjective: To expand existing knowledge on gait parameters in a healthy population using a baropodometer and to ensure the reliability of the equipment.
Silvia Iovine Kobata +3 more
doaj +1 more source
Benchmarking urine storage and collection conditions for evaluating the female urinary microbiome. [PDF]
, 2019 Standardized conditions for collection, preservation and storage of urine for microbiome research have not been established. We aimed to identify the effects of the use of preservative AssayAssure® (AA), and the effects of storage time and temperatures ...
Brubaker, Linda +8 more
core
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
A framework to characterise the reproducibility of meta‐analysis results with its application to direct oral anticoagulants in the acute treatment of venous thromboembolism [PDF]
, 2023 Céline Chapelle +4 more
openalex +1 more source
Reproducibility of liquid oxygen impact test results [PDF]
Results for 12,000 impacts on a wide range of materials were studied to determine the reproducibility of the liquid oxygen impact test method. Standard deviations representing the overall variability of results were in close agreement with the expected ...
Gayle, J. B.
core +1 more source