Results 151 to 160 of about 1,417,965 (314)

Improving Reproducibility and Reuse of Modelling Results in the Life Sciences

, 2018
Research results are complex and include a variety of heterogeneous data. This entails major computational challenges to (i) to manage simulation studies, (ii) to ensure model exchangeability, stability and validity, and (iii) to foster communication between partners.
openaire   +3 more sources

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Active Mixing During Hybridization Improves the Accuracy and Reproducibility of Microarray Results

, 2005
Christopher J. Schaupp, Guojian Jiang, Timothy G. Myers, Michael A. Wilson   +3 more
openalex   +1 more source

Cornea Thermography: Optimal Evaluation of the Outcome and the Resulting Reproducibility [PDF]

, 2018
Katarzyna Konieczka, Andreas Schoetzau, Simone Koch, Daniela Hauenstein, Josef Flammer   +4 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Multisite Reproducibility of Results Obtained by the Broth Microdilution Method for Susceptibility Testing ofMycobacterium abscessus, Mycobacterium chelonae, and Mycobacterium fortuitum

Journal of Clinical Microbiology, 1999
G. Woods, J. S. Bergmann, F. Witebsky, G. Fahle, A. Wanger, Betty Boulet, M. Plaunt, B. A. Brown, R. Wallace   +8 more
semanticscholar   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Detection of Pathogenic Protozoa in the Diagnostic Laboratory: Result Reproducibility, Specimen Pooling, and Competency Assessment

, 2008
Michael Libman, T. W. Gyorkos, Evelyne Kokoskin, J. D. MacLean   +3 more
openalex   +1 more source

Making simulation results reproducible—Survey, guidelines, and examples based on Gradle and Docker [PDF]

, 2019
Wilfried Elmenreich, Philipp Moll, Sebastian Theuermann, Mathias Lux   +3 more
openalex   +1 more source

Analytical Sensitivity, Reproducibility of Results, and Clinical Performance of Five PCR Assays for Detecting Chlamydia pneumoniae DNA in Peripheral Blood Mononuclear Cells

Journal of Clinical Microbiology, 2000
James B. Mahony, James B. Mahony, Sylvia Chong, B. K. Coombes, Marek Smieja, A. Petrich, A. Petrich   +6 more
semanticscholar   +1 more source