Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Introduction to Reproducible Geospatial Analysis and Figures in R: A Tutorial Article
The present article is intended to serve an educational purpose for data scientists and students who already have experience with the R language and which to start using it for geospatial analysis and map creation.
Philippe Maesen, Edouard Salingros
doaj +1 more source
Pragmatic reproducible research: improving the research process from raw data to results, bit by bit. [PDF]
Rasmussen LV, Whitley EW, Welty LJ.
europepmc +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The Riffomonas YouTube Channel: An Educational Resource To Foster Reproducible Research Practices. [PDF]
Schloss PD.
europepmc +1 more source
Reproducibility of Research During COVID‐19: Examining the Case of Population Density and the Basic Reproductive Rate from the Perspective of Spatial Analysis [PDF]
Antonio Páez
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Toward practical transparent verifiable and long-term reproducible research using Guix. [PDF]
Vallet N, Michonneau D, Tournier S.
europepmc +1 more source
Evaluating the Generalizability and Reproducibility of Scientific Research [PDF]
Sue S. Yom +5 more
openalex +1 more source

