Results 1 to 10 of about 739,587 (347)

Metformin in Reproductive Biology [PDF]

Frontiers in Endocrinology, 2018
Initially produced in Europe in 1958, metformin is still one of the most widely prescribed drugs to treat type II diabetes and other comorbidities associated with insulin resistance.
Melanie Faure, Michael J. Bertoldo, Rita Khoueiry, Alice Bongrani, François Brion, Cecilia Giulivi, Cecilia Giulivi, Joelle Dupont, Pascal Froment   +8 more
doaj   +9 more sources

Extracellular vesicles in reproductive biology and disorders: a comprehensive review. [PDF]

Front Endocrinol (Lausanne)
Wang J, Wang D, Zhang Y, Sun P, Yi L, Han A, Zhao W, Zhang Y, Ma H.   +8 more
europepmc   +3 more sources

Reproductive biology of female common dolphins (Delphinus delphis) in New Zealand waters. [PDF]

Mar Biol, 2022
Palmer EI, Betty EL, Murphy S, Perrott MR, Smith ANH, Stockin KA.   +5 more
europepmc   +3 more sources

The lipase cofactor CGI58 controls placental lipolysis

JCI Insight, 2023
In eutherians, the placenta plays a critical role in the uptake, storage, and metabolism of lipids. These processes govern the availability of fatty acids to the developing fetus, where inadequate supply has been associated with substandard fetal growth.
Jennifer Guerrero-Santoro, Mayumi Morizane, Soo-Young Oh, Takuya Mishima, Julie P. Goff, Ibrahim Bildirici, Elena Sadovsky, Yingshi Ouyang, Vladimir A. Tyurin, Yulia Y. Tyurina, Valerian E. Kagan, Yoel Sadovsky   +11 more
doaj   +1 more source

Fetal maturation revealed by amniotic fluid cell-free transcriptome in rhesus macaques

JCI Insight, 2022
Accurate estimate of fetal maturity could provide individualized guidance for delivery of complicated pregnancies. However, current methods are invasive, have low accuracy, and are limited to fetal lung maturation.
Augusto F. Schmidt, Daniel J. Schnell, Kenneth P. Eaton, Kashish Chetal, Paranthaman S. Kannan, Lisa A. Miller, Claire A. Chougnet, Daniel T. Swarr, Alan H. Jobe, Nathan Salomonis, Beena D. Kamath-Rayne   +10 more
doaj   +1 more source

X-linked RBBP7 mutation causes maturation arrest and testicular tumors

The Journal of Clinical Investigation, 2023
Maturation arrest (MA) is a subtype of non-obstructive azoospermia, and male infertility is a known risk factor for testicular tumors. However, the genetic basis for many affected individuals remains unknown.
Jingping Li, Huimei Zheng, Jiaru Hou, Jianhua Chen, Fengbin Zhang, Xiaohang Yang, Fan Jin, Yongmei Xi   +7 more
doaj   +1 more source

Maternal CXCR4 deletion results in placental defects and pregnancy loss mediated by immune dysregulation

JCI Insight, 2023
CXCR4 is a key regulator of the development of NK cells and DCs, both of which play an important role in early placental development and immune tolerance at the maternal-fetal interface. However, the role of CXCR4 in pregnancy is not well understood. Our
Fang Lyu, Chase Burzynski, Yuan yuan Fang, Aya Tal, Alice Y. Chen, Jacqueline Kisa, Kriti Agrawal, Yuval Kluger, Hugh S. Taylor, Reshef Tal   +9 more
doaj   +1 more source

Maternal PlGF and umbilical Dopplers predict pregnancy outcomes at diagnosis of early-onset fetal growth restriction

The Journal of Clinical Investigation, 2023
BACKGROUND Severe, early-onset fetal growth restriction (FGR) causes significant fetal and neonatal mortality and morbidity. Predicting the outcome of affected pregnancies at the time of diagnosis is difficult, thus preventing accurate patient counseling.
Rebecca Spencer, Kasia Maksym, Kurt Hecher, Karel Maršál, Francesc Figueras, Gareth Ambler, Harry Whitwell, Nuno Rocha Nené, Neil J. Sebire, Stefan R. Hansson, Anke Diemert, Jana Brodszki, Eduard Gratacós, Yuval Ginsberg, Tal Weissbach, Donald M. Peebles, Ian Zachary, Neil Marlow, Angela Huertas-Ceballos, Anna L. David   +19 more
doaj   +1 more source

Nectaries and reproductive biology of croton sarcopetalus (euphorbiaceae) [PDF]

, 2001
Flower morphology, nectary structure, nectar chemical composition, breeding system, floral visitors and pollination were analysed in Croton sarcopetalus, a diclinous-monoecious shrub from Argentina.
Bernardello, Gabriel Luis Mario, Freitas, Leandro, Galetto, Leonardo, Paoli, Adelita   +3 more
core   +1 more source

Macrophages exert homeostatic actions in pregnancy to protect against preterm birth and fetal inflammatory injury

JCI Insight, 2021
Macrophages are commonly thought to contribute to the pathophysiology of preterm labor by amplifying inflammation — but a protective role has not previously been considered to our knowledge. We hypothesized that given their antiinflammatory capability in
Nardhy Gomez-Lopez, Valeria Garcia-Flores, Peck Yin Chin, Holly M. Groome, Melanie T. Bijland, Kerrilyn R. Diener, Roberto Romero, Sarah A. Robertson   +7 more
doaj   +1 more source