Results 11 to 20 of about 1,879,235 (344)
Fetal maturation revealed by amniotic fluid cell-free transcriptome in rhesus macaques
JCI Insight, 2022 Accurate estimate of fetal maturity could provide individualized guidance for delivery of complicated pregnancies. However, current methods are invasive, have low accuracy, and are limited to fetal lung maturation.
Augusto F. Schmidt +10 more
doaj +1 more source
X-linked RBBP7 mutation causes maturation arrest and testicular tumors
The Journal of Clinical Investigation, 2023 Maturation arrest (MA) is a subtype of non-obstructive azoospermia, and male infertility is a known risk factor for testicular tumors. However, the genetic basis for many affected individuals remains unknown.
Jingping Li +7 more
doaj +1 more source
JCI Insight, 2023 CXCR4 is a key regulator of the development of NK cells and DCs, both of which play an important role in early placental development and immune tolerance at the maternal-fetal interface. However, the role of CXCR4 in pregnancy is not well understood. Our
Fang Lyu +9 more
doaj +1 more source
It takes two to tango: including a female perspective in reproductive biology.
Integrative and Comparative Biology, 2020 Like many scientific disciplines, the field of reproductive biology is subject to biases in terminology and research foci. For example, females are often described as the coy and passive players in reproductive behaviors and are termed 'promiscuous' if ...
Teri J Orr +14 more
semanticscholar +1 more source
JCI Insight, 2021 Clinical phenotyping of term and preterm labor is imprecise, and disagreement persists on categorization relative to underlying pathobiology, which remains poorly understood.
William E. Ackerman IV +5 more
doaj +1 more source
The Journal of Clinical Investigation, 2023 BACKGROUND Severe, early-onset fetal growth restriction (FGR) causes significant fetal and neonatal mortality and morbidity. Predicting the outcome of affected pregnancies at the time of diagnosis is difficult, thus preventing accurate patient counseling.
Rebecca Spencer +19 more
doaj +1 more source
JCI Insight, 2021 Macrophages are commonly thought to contribute to the pathophysiology of preterm labor by amplifying inflammation — but a protective role has not previously been considered to our knowledge. We hypothesized that given their antiinflammatory capability in
Nardhy Gomez-Lopez +7 more
doaj +1 more source
Breakthroughs and new horizons in reproductive biology of rare and endangered animal species
Biology of Reproduction, 2019 Because of higher extinction rates due to human and natural factors, more basic and applied research in reproductive biology is required to preserve wild species and design proper strategies leading to sustainable populations. The objective of the review
P. Comizzoli, W. Holt
semanticscholar +1 more source
Placental dysfunction influences fetal monocyte subpopulation gene expression in preterm birth
JCI Insight, 2022 The placenta is the primary organ for immune regulation, nutrient delivery, gas exchange, protection against environmental toxins, and physiologic perturbations during pregnancy.
Abhineet M. Sharma +9 more
doaj +1 more source
Mitochondria Biology in Reproductive Function
Antioxidants, 2022 Mitochondria are multitasking organelles involved in the maintenance of cell homeostasis [...]
Carla Tatone, Giovanna Di Emidio
doaj +1 more source