Results 221 to 230 of about 739,587 (347)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

A Practical Guide to Avoiding Biased Communication in Reproductive Biology. [PDF]

Integr Comp Biol
Baker Z, Hayssen V.
europepmc   +1 more source

Fossil bacula of five species of Borophaginae (Family: Canidae): Implications for their reproductive biology. [PDF]

PLoS One, 2023
Varajão de Latorre D.
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Reproductive biology and conservation status of <i>Leopoldia mira</i>, <i>Muscari sandrasicum</i> and <i>M. serpentinicum</i> (Asparagaceae). [PDF]

Biodivers Data J
Çon O, Çiçek M.
europepmc   +1 more source

Taxonomy and reproductive biology of southern Australian representatives of the Gigartinaceae (Gigartinales, Rhodophyta) / Karen Susan Edyvane

, 1989
Karen S. Edyvane
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Reproductive biology of invasive grass carp (Ctenopharyngodon idella) in two North American systems. [PDF]

J Fish Biol
Wilson TM, Acre MR, Williams F, Calfee RD, Mayer CM, Mapes RL, Kemp CM, Young RT, Byrne ME.   +8 more
europepmc   +1 more source

Solar radiation, temperature and the reproductive biology of the coral Lobactis scutaria in a changing climate. [PDF]

Sci Rep, 2023
Bouwmeester J, Daly J, Zuchowicz N, Lager C, Henley EM, Quinn M, Hagedorn M.   +6 more
europepmc   +1 more source

Sex expression and reproductive biology in a tree species, Fraxinus excelsior L

, 2013
Béatrice Albert, Marie-Élise Morand-Prieur, Stéphanie Brachet, Pierre-Henri Gouyon, Nathalie Frascaria‐Lacoste, Christian Raquin   +5 more
openalex   +2 more sources