Results 21 to 30 of about 739,587 (347)

Loss-of-function mutations in CFAP57 cause multiple morphological abnormalities of the flagella in humans and mice

open access: yesJCI Insight, 2023
Multiple morphological abnormalities of the sperm flagella (MMAF) are the most severe form of asthenozoospermia due to impaired axoneme structure in sperm flagella. Dynein arms are necessary components of the sperm flagellar axoneme.
Ao Ma   +23 more
doaj   +1 more source

A review of the reproductive system in anuran amphibians

open access: yesZoological Letters, 2023
Reproductive biology is an important topic that is well explored in many vertebrates, but information about frogs’ reproductive mechanisms could be improved.
Maribel Méndez-Tepepa   +3 more
doaj   +1 more source

WNK1 regulates uterine homeostasis and its ability to support pregnancy

open access: yesJCI Insight, 2020
WNK1 (with no lysine [K] kinase 1) is an atypical kinase protein ubiquitously expressed in humans and mice. A mutation in its encoding gene causes hypertension in humans, which is associated with abnormal ion homeostasis.
Ru-pin Alicia Chi   +6 more
doaj   +1 more source

Transcriptome and DNA methylome analyses reveal underlying mechanisms for the racial disparity in uterine fibroids

open access: yesJCI Insight, 2022
Uterine fibroids (leiomyomas) affect Black women disproportionately compared with women of other races and ethnicities in terms of prevalence, incidence, and severity of symptoms. The causes of this racial disparity are essentially unknown.
Emmanuel N. Paul   +10 more
doaj   +1 more source

ARRDC5 expression is conserved in mammalian testes and required for normal sperm morphogenesis

open access: yesNature Communications, 2023
In sexual reproduction, sperm contribute half the genomic material required for creation of offspring yet core molecular mechanisms essential for their formation are undefined.
Mariana I. Giassetti   +8 more
doaj   +1 more source

A single-cell atlas of the myometrium in human parturition

open access: yesJCI Insight, 2022
Parturition is a well-orchestrated process characterized by increased uterine contractility, cervical ripening, and activation of the chorioamniotic membranes; yet, the transition from a quiescent to a contractile myometrium heralds the onset of labor ...
Roger Pique-Regi   +18 more
doaj   +1 more source

Radiotherapy exposure directly damages the uterus and causes pregnancy loss

open access: yesJCI Insight, 2023
Female cancer survivors are significantly more likely to experience infertility than the general population. It is well established that chemotherapy and radiotherapy can damage the ovary and compromise fertility, yet the ability of cancer treatments to ...
Meaghan J. Griffiths   +17 more
doaj   +1 more source

Evolutionary processes from the perspective of flowering time diversity. [PDF]

open access: yes, 2020
Although it is well appreciated that genetic studies of flowering time regulation have led to fundamental advances in the fields of molecular and developmental biology, the ways in which genetic studies of flowering time diversity have enriched the field
Blackman, Benjamin K, Gaudinier, Allison
core   +1 more source

Notes on the Reproductive Biology of the Alabama Red Hills Salamander (Phaeognathus hubrichti ) [PDF]

open access: yes, 2003
Living Amphibia exhibit two major life history modes, possession of an aquatic larval stage or direct development, with the latter assumed to be the derived evolutionary condition (Duellman and Trueb 1986, Wake 1989).
Means, Bruce
core   +2 more sources

Implications of fisheries during the spawning season for the sustainable management and recovery of depleted fish stocks: a conceptual framework [PDF]

open access: yes, 2009
Fishing during the spawning season may negatively affects the reproductive potential and reproductive dynamics of exploited fish stocks due to a variety of mechanisms such as the disturbance of the natural spawning behaviour, effects on the age, size and
Rijnsdorp, A.D.
core   +1 more source

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