Results 41 to 50 of about 739,587 (347)

Antigen-specific decidual CD8+ T cells include distinct effector memory and tissue-resident memory cells

JCI Insight, 2023
Maternal decidual CD8+ T cells must integrate the antithetical demands of providing immunity to infection while maintaining immune tolerance for fetal and placental antigens.
Shweta Mahajan, Aria Alexander, Zachary Koenig, Nicholas Saba, Nina Prasanphanich, David A. Hildeman, Claire A. Chougnet, Emily DeFranco, Sandra Andorf, Tamara Tilburgs   +9 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reproductive Biology of Charybdis hellerii in Lasongko and Kendari Bays, Southeast Sulawesi, Indonesia [PDF]

, 2021
Abdul Hamid et al.
openalex   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Reproductive biology of penaeid prawns [PDF]

, 1983
In the contemporary period, knowledge of different aspects of reproduction in penaeid prawns is increasingly applied to improve their capture and culture fisheries.
Rao, P Vedavyasa
core  

Leptin receptor in the chicken ovary: potential involvement in ovarian dysfunction of ad libitum-fed broiler breeder hens [PDF]

, 2004
In hens, the ovarian follicles committed to ovulation are arranged in an ordered follicular hierarchy. In standard broiler breeders hens genetically selected for high growth rate the reproductive function is clearly dysfunctional.
Cassy, Sandrine, Collin, Anne, Crochet, Sabine, Metayer, Sonia, Rideau, Nicole, Tesseraud, Sophie   +5 more
core   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Reproductive Biology of Largehead Hairtails, Trichiurus Lepturus Linnaeus, 1758 in the Coastal Area of Bantul Regency [PDF]

, 2017
Ikan layur (Trichiurus lepturus) merupakan salah satu komoditas hasil tangkapan ikan di Daerah Istimewa Yogyakarta dengan jumlah produksi dan nilai yang tinggi.
Djumanto, D. (Djumanto), Murwantoko, M. (Murwantoko), Novianingrum, P. (Praditha), Setyobudi, E. (Eko)   +3 more
core  

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Fidgetin-like 2 negatively regulates axonal growth and can be targeted to promote functional nerve regeneration

JCI Insight, 2021
The microtubule (MT) cytoskeleton plays a critical role in axon growth and guidance. Here, we identify the MT-severing enzyme fidgetin-like 2 (FL2) as a negative regulator of axon regeneration and a therapeutic target for promoting nerve regeneration ...
Lisa Baker, Moses Tar, Adam H. Kramer, Guillermo A. Villegas, Rabab A. Charafeddine, Olga Vafaeva, Parimala Nacharaju, Joel Friedman, Kelvin P. Davies, David J. Sharp   +9 more
doaj   +1 more source