YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Facing an Epidemic: An Analysis of HIV/AIDS, Antiretroviral Drug, and International Response to the AIDS Pandemic [PDF]
More than 33 million people are living with HIV/AIDS around the globe with 68% of all cases occurring in sub-Saharan Africa. The global prevalence rate is shocking considering that the disease was relatively unknown just 30 years ago.
Tate, Michael
core +1 more source
Economic implications of assisted reproductive techniques: a systematic review [PDF]
L. Garceau
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
The effect of vitamin D on the assisted reproductive techniques (ART) outcomes: A narrative review [PDF]
Introduction: Infertility is a global health concern and the prevalence of vitamin D deficiency in the infertile population is 27% to 65%. The role of vitamin D is proposed with the expression of receptors in all types of human reproductive tissues in ...
Mitra Savabi Esfahani +2 more
doaj +1 more source
Effects of duration of water stress at different growth stages on growth and yield of soybeans (Glycine max (L) Merrill) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agriculture in Plant Science at Massey University [PDF]
Four soybean cultivars (viz. Evans, Geiso, Maple Arrow and S.J.4) were subjected to water stress at three different reproductive growth stages: i)entire reproductive growth stages (R1 to R7) ii) early reproductive growth stages (R1 to R4) and iii) late ...
Laohasiriwong, Suwit
core
Follicular flushing during oocyte retrieval in assisted reproductive techniques [PDF]
Supreeya Wongtra‐ngan +2 more
openalex +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Experimental population suppression of Richardson's ground squirrels (Spermophilus richardsonii) in Alberta [PDF]
Richardson's ground squirrel is one of the most economically harmful rodents in east central Alberta. In an effort to develop an effective, safe, economical and practical method of long-term population control over large areas, experimental field testing
Alsager, D. E.
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source

