Results 61 to 70 of about 1,385,080 (304)

Genetic and phenotypic relationships among endocrine and traditional fertility traits and production traits in Holstein-Friesian dairy cows [PDF]

, 2002
The objective of this study was to estimate the heritability of a number of traditional and endocrine fertility traits in addition to d-56 predicted milk yield (MY56), and the genetic and phenotypic correlations between these traits.
Royal, M.D., Flint, A.P.F., Woolliams, John   +2 more
core  

Genetic Evaluation of Body Condition Score, Reproductive Performance and Blood Parameters in Shami Goat [PDF]

Tikrit Journal for Agricultural Sciences
This study was conducted at the Ruminant Research Station of the Ministry of Agriculture using 50 Shami goats aged 2-3 years, aimed at studying the relationship between BCS and reproductive performance and haematological parameters in goats, as well as ...
Noor Flayyih, H. Al-janabi, Ali Abdullah
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Inbreeding depression in male reproductive traits

Journal of Evolutionary Biology
Abstract Inbreeding frequently leads to inbreeding depression, a general reduction in trait values and loss of fitness, and it appears that some sexually selected traits are especially sensitive to inbreeding, but sperm may be an exception.
Ramakrishnan Vasudeva, Kris Sales, Matthew J G Gage, David J Hosken   +3 more
openaire   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Comparison of genomic predictions for carcass and reproduction traits in Berkshire, Duroc and Yorkshire populations in Korea [PDF]

Asian-Australasian Journal of Animal Sciences, 2019
Objective A genome-based best linear unbiased prediction (GBLUP) method was applied to evaluate accuracies of genomic estimated breeding value (GEBV) of carcass and reproductive traits in Berkshire, Duroc and Yorkshire populations in Korean swine ...
Asif Iqbal, Tae-Jeong Choi, You-Sam Kim, Yun-Mi Lee, M. Zahangir Alam, Jong-Hyun Jung, Ho-Sung Choe, Jong-Joo Kim   +7 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Prenatal versus postnatal sex steroid hormone effects on autistic traits in children at 18 to 24 months of age [PDF]

, 2012
Background Studies of prenatal exposure to sex steroid hormones predict autistic traits in children at 18 to 24 and at 96 months of age. However, it is not known whether postnatal exposure to these hormones has a similar effect.
Simon Baron-Cohen, Kevin Taylor, Thomson, Lynn, O’donnell, Kieran J, Jag Ahluwalia, Bonnie Auyeung, Thomson Lynn, Hackett Gerald, Lynn Thomson, Gerald Hackett, Ahluwalia Jag, Hackett, Gerald, Ahluwalia, Jag, Baron-cohen, Simon, O’Donnell Kieran J, Auyeung Bonnie, Kieran J O’Donnell, Baron-Cohen Simon, Auyeung, Bonnie; id_orcid, Taylor, Kevin, Taylor Kevin   +20 more
core   +3 more sources

Genome-Wide Association Study Reveals Candidate Genes Underlying Reproduction-Associated Conformation Traits in Jersey Cattle

Agriculture
Reproductive traits are essential in dairy cattle breeding, and improving body conformation is considered beneficial for reproductive performance. This study systematically analyzed the genetic relationships between six key conformation traits—stature ...
Tianqi Zhao, Hui Jiang, Hao Zhu, Zhijian Zhu, Zeliang Huang, Zhaoying Song, Mudasir Nazar, Xubin Lu, Zhangping Yang   +8 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source