Results 61 to 70 of about 2,104,193 (346)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic analysis for reproductive and longevity traits in Landlly sows

Indian Journal of Animal Sciences
The rate of reproduction and lifetime productivity of the animals determine the success of a herd. As these features significantly impact sow productivity, welfare, and profitability, there is considerable interest in global swine breeding programmes to
CHHAYA RANI, ANUJ CHAUHAN, INDRASEN CHAUHAN, SAKSHI VAISHNAV, ARGANA AJAY K, SNEHASMITA PANDA, BHARAT BHUSHAN, TRIVENI DUTT   +7 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Fertility of boars: What is important to know [PDF]

Biotechnology in Animal Husbandry, 2017
The most important part in reproductive management is the control of boar fertility. A common division of fertility traits is on the: in vitro (sperm traits) and in vivo (return rate, farrowing rate and litter size traits) fertility. In many studies were
Savić Radomir, Ausejo Marcos Raquel, Petrović Milica, Radojković Dragan, Radović Čedomir, Gogić Marija   +5 more
doaj  

The Olive tree from juvenility to maturity: Insight on the developmental changes over years and the genetic basis of vegetative and reproductive traits : W304 [PDF]

, 2013
Fruit trees productivity is closely linked to their development. Integrating architectural traits in breeding programs could optimise cultivation management and improve bearing regularity.
Ben Sadok, Inès, Costes, Evelyne, Garcia, Gilbert, Khadari, Bouchaib, Moutier, Nathalie   +4 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Analysis of reproductive performances during the formation of a synthetic rabbit strain

, 2005
[EN] In 1995, a synthetic rabbit strain ('2666') was formed at INRA for commercial meat purposesby crossing the INRA '2066' strain and the 'V' strain from the Polytechnical University of Valencia (Spain).The development of some reproductive traits and ...
Baselga, M., Brun, J.M.
core   +1 more source

Inter-population variability in the reproductive morphology of the shore crab (Carcinus maenas): Evidence of endocrine disruption in a marine crustacean? [PDF]

, 2005
Environmental contaminants that are capable of causing endocrine disrupting effects are currently a major cause for concern. These chemicals are known to influence the reproductive development of vertebrates by mimicking or antagonising the actions of ...
Brian, JV
core   +1 more source

Inbreeding depression in male reproductive traits

Journal of Evolutionary Biology
Abstract Inbreeding frequently leads to inbreeding depression, a general reduction in trait values and loss of fitness, and it appears that some sexually selected traits are especially sensitive to inbreeding, but sperm may be an exception.
Ramakrishnan Vasudeva, Kris Sales, Matthew J G Gage, David J Hosken   +3 more
openaire   +2 more sources