Results 71 to 80 of about 2,104,193 (346)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Herbivores and plant defences affect selection on plant reproductive traits more strongly than pollinators

Journal of Evolutionary Biology, 2018
Pollinators and herbivores can both affect the evolutionary diversification of plant reproductive traits. However, plant defences frequently alter antagonistic and mutualistic interactions, and therefore, variation in plant defences may alter patterns of
James S. Santangelo, K. Thompson, Marc T. J. Johnson   +2 more
semanticscholar   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Mapping quantitative trait loci for heat tolerance of reproductive traits in tomato (Solanum lycopersicum)

Molecular breeding, 2017
Global warming has become a worldwide concern due to its adverse effects on agricultural output. In particular, long-term mildly high temperatures interfere with sexual reproduction and thus fruit and seed set.
Jiemeng Xu, Nicky Driedonks, M. Rutten, W. Vriezen, G. de Boer, I. Rieu   +5 more
semanticscholar   +1 more source

Reproductive traits of Cyrtorrhinus lividipennis REUTER.

Kyushu Plant Protection Research, 1996
Developmental speed and reproductive potential of the mirid bug, Cyrtorrhinus lividipennis, were measured nuder laboratory conditions. Both nymphs and adults were supplied with rice plants onto which gravid females of Nilaparvata lugens were released.
Yoshito SUZUKI, Koichi TANKA
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Genome-Wide Association Study Reveals Candidate Genes Underlying Reproduction-Associated Conformation Traits in Jersey Cattle

Agriculture
Reproductive traits are essential in dairy cattle breeding, and improving body conformation is considered beneficial for reproductive performance. This study systematically analyzed the genetic relationships between six key conformation traits—stature ...
Tianqi Zhao, Hui Jiang, Hao Zhu, Zhijian Zhu, Zeliang Huang, Zhaoying Song, Mudasir Nazar, Xubin Lu, Zhangping Yang   +8 more
doaj   +1 more source

A Novel c.100C > G Mutation in the Gene and Its Relation With the Reproductive Traits of Awassi Ewes

Bioinformatics and Biology Insights, 2023
Reproductive traits are affected by many factors, including ovarian function, hormones, and genetics. Genetic polymorphisms of candidate genes are associated with reproductive traits. Several candidate genes are associated with economic traits, including
Tahreer M Al-Thuwaini, Wefak J Albazi, Mohammed Baqur S Al-Shuhaib, Layth H Merzah, Rihab G Mohammed, Fadhil A Rhadi, Ali B Abd Al-Hadi, Ahmed H Alkhammas   +7 more
doaj   +1 more source

Spatial connectedness imposes local‐ and metapopulation‐level selection on life history through feedbacks on demography

, 2020
Dispersal evolution impacts the fluxes of individuals and hence, connectivity in metapopulations. Connectivity is therefore decoupled from the structural connectedness of the patches within the spatial network.
Helle W., Johst K., Li X.‐Y., Rossetti M.R., Rudnick D.   +4 more
core   +1 more source