Results 251 to 260 of about 358,538 (335)

Plastic hepatocyte states limit liver cancer development. [PDF]

Nat Commun
Strathearn LS, Hayata Y, Illendula A, Hewett CK, Chen M, He G, Escribano-Cebrián M, Jarboe B, Gómez-Tomé L, de Prisco N, Slifker M, Kawamura S, Nakagawa H, Rossell D, Stanger BZ, Font-Burgada J.   +15 more
europepmc   +1 more source

Developmental reprogramming in melanocortin neurons modulates diet-induced obesity in mice

Xu, Baijie
openalex   +1 more source

Transcriptional landscape of direct reprogramming toward hematopoietic stem cells [PDF]

Cooper Stansbury, Jillian Cwycyshyn, Sarah Golts, Walter Meixner, Joshua Pickard, Walter Meixner, Indika Rajapakse, Lindsey A. Muir   +7 more
openalex   +1 more source

CellPolaris: Transfer Learning for Gene Regulatory Network Construction to Guide Cell State Transitions

Advanced Science, EarlyView.
CellPolaris decodes how transcription factors guide cell fate by building gene regulatory networks from transcriptomic data using transfer learning. It generates tissue‐ and cell‐type‐specific networks, identifies master regulators in cell state transitions, and simulates TF perturbations in developmental processes.
Guihai Feng, Xin Qin, Jiahao Zhang, Wuliang Huang, Yiyang Zhang, Wentao Cui, Yao Chen, Shirui Li, Wenhao Liu, Yao Tian, Yana Liu, Jingxi Dong, Ping Xu, Zhenpeng Man, Guole Liu, Zhongming Liang, Xinlong Jiang, Xiaodong Yang, Pengfei Wang, Ge Yang, Hongmei Wang, Xuezhi Wang, Ming‐Han Tong, Yuanchun Zhou, Shihua Zhang, Yiqiang Chen, Yong Wang, Xin Li   +27 more
wiley   +1 more source

From metabolic alterations to chronic inflammation: mechanisms and immunoregulation of metabolic reprogramming in COPD. [PDF]

Front Immunol
Zeng S, Zhang Y, Li S, Li Z, Li P, Xie J, Zhang J, Xie L, Yang Y.   +8 more
europepmc   +1 more source

A Shape‐Adaptive, Performance‐Programmable, Self‐Healable and On‐Demand Destructible Robotic Skin via Self‐Strengthening Dynamic Silicone

Advanced Science, EarlyView.
Enabled by the distinctive inter‐ and intra‐chain siloxane exchange in commercially available silicones as the dielectric layer, the omni‐adaptive robotic skin (OmniAdapt) integrates multiple advanced functionalities: programmable sensing performance via the self‐stiffening dielectric material, application as BPM sensor, shape adaptivity for electronic
Wusha Miao, Lara S. Laamari, Jing Yu, Sanjay Schreiber, Lukas Heer, Jiacheng Cui, Jiayuan Huang, Hedan Bai   +7 more
wiley   +1 more source

Decoding the HIF-1-driven metabolic-inflammatory-immune axis in sepsis-associated lung injury: a comprehensive overview. [PDF]

Front Immunol
Zhang S, Hu B, Fang Y, Liu M, Liu Q, Chen Y, Zhou J.   +6 more
europepmc   +1 more source

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

Advanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan, Natan Roberto de Barros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, Xiangsheng Huang, Faraz Bishehsari   +11 more
wiley   +1 more source

Metabolic reprogramming in clear cell renal cell carcinoma: core pathways and targeted therapeutic strategies. [PDF]

Front Genet
Zhan M, Zhao B, Chen H, Wu J, Shi R, Gao F, Zhao L, Zhu J.   +7 more
europepmc   +1 more source