Results 51 to 60 of about 238,286 (345)

Epigenetic impairments in development of parthenogenetic preimplantation mouse embryos

The Journal of Reproduction and Development, 2018
Parthenogenesis is an activation process of oocytes that occur without the participation of sperm. Evidence suggests that normal development of embryos requires proper expression of several imprinted genes inherited from both the paternal and maternal ...
Ngan Thi Kim HO, Thuy Van Thi NGUYEN, Thuan Van NGUYEN, Hong-Thuy BUI   +3 more
doaj   +1 more source

Deterministic reprogramming of neutrophils within tumors

Science
Neutrophils are increasingly recognized as key players in the tumor immune response and are associated with poor clinical outcomes. Despite recent advances characterizing the diversity of neutrophil states in cancer, common trajectories and mechanisms ...
M. Ng, Immanuel Kwok, Leonard Tan, Changming Shi, Daniela Cerezo-Wallis, Yingrou Tan, K. Leong, Gabriel F. Calvo, Katharine Yang, Yuning Zhang, Jingsi Jin, K. Liong, Dandan Wu, Rui He, Dehua Liu, Ye Chean Teh, Camille Blériot, N. Caronni, Zhaoyuan Liu, Kaibo Duan, V. Narang, Iván Ballesteros, Federica Moalli, Mengwei Li, Jinmiao Chen, Yao Liu, Lianxin Liu, Jingjing Qi, Yingbin Liu, Lingxi Jiang, Baiyong Shen, Hui Cheng, T. Cheng, Veronique Angeli, Ankur Sharma, Y. Loh, H. Tey, Shu Zhen Chong, M. Iannacone, R. Ostuni, Andrés Hidalgo, F. Ginhoux, L. Ng   +42 more
semanticscholar   +1 more source

Trained Immunity: Reprogramming Innate Immunity in Health and Disease.

Annual Review of Immunology, 2021
Traditionally, the innate and adaptive immune systems are differentiated by their specificity and memory capacity. In recent years, however, this paradigm has shifted: Cells of the innate immune system appear to be able to gain memory characteristics ...
S. Bekkering, Jorge Domínguez-Andrés, L. Joosten, N. Riksen, M. Netea   +4 more
semanticscholar   +1 more source

Enzymatic isolation of porcine preantral follicles impairs oocyte viability and long-term in vitro growth

The Journal of Reproduction and Development
The enzymatic isolation of preantral follicles (PAFs) is considered the most efficient method for retrieving a large number of intact follicles, offering significant advantages in terms of yield and processing time.
Ba Anh My LE, Lien Boi Linh NGUYEN, Phuong Thanh NGUYEN, Ha Nhat Lam VO, Ngoc Song Thu TRAN, Bao Nghi TRAN, Ngoc Thao Vy NGUYEN, Chi Thien LAM, Nhat-Thinh NGUYEN, Van Thuan NGUYEN, Hong-Thuy BUI   +10 more
doaj   +1 more source

Autophagosome Biogenesis

Cells, 2023
Autophagy–the lysosomal degradation of cytoplasm–plays a central role in cellular homeostasis and protects cells from potentially harmful agents that may accumulate in the cytoplasm, including pathogens, protein aggregates, and dysfunctional organelles ...
Yan Zhen, Harald Stenmark
doaj   +1 more source

Anti-Cancer Effects of Lactobacillus plantarum L-14 Cell-Free Extract on Human Malignant Melanoma A375 Cells

Molecules, 2020
Human malignant melanoma is the most aggressive type of skin cancer with high metastatic ability. Despite several traditional therapies, the mortality rate remains high. Lactobacillus plantarum (L.
Jaehyun Park, Mijin Kwon, Jaehoon Lee, Sangkyu Park, Jeongmin Seo, Sangho Roh   +5 more
doaj   +1 more source

High Therapeutic and Esthetic Properties of Extracellular Vesicles Produced from the Stem Cells and Their Spheroids Cultured from Ocular Surgery-Derived Waste Orbicularis Oculi Muscle Tissues

Antioxidants, 2021
Extracellular vesicles (EVs) are paracrine factors that mediate stem cell therapeutics. We aimed at evaluating the possible therapeutic and esthetic applications of EVs prepared from the waste human facial tissue-derived orbicularis oculi muscle stem ...
Kyung Min Lim, Ahmed Abdal Dayem, Yujin Choi, Yoonjoo Lee, Jongyub An, Minchan Gil, Soobin Lee, Hee Jeong Kwak, Balachandar Vellingirl, Hyun Jin Shin, Ssang-Goo Cho   +10 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Reprogramming the Genetic Code [PDF]

Science, 2011
Incorporating unnatural amino acids into proteins presents challenges in expanding the genetic code.
openaire   +3 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source