The Biophysical Micro-Environment's Influence on Cell Fate Decisions During Macrophage Activation and Somatic Cell Reprogramming [PDF]
Cells are known to sense and respond to their mechanical microenvironment in profound ways. Various evidence has implicated the adhesome, a body of adhesion associated proteins, in several cell fate decisions, including differentiation and proliferation.
arxiv
Corrigendum: Deepening the understanding of CNVs on chromosome 15q11–13 by using hiPSCs: An overview
Angela Maria Giada Giovenale+11 more
doaj +1 more source
Cellular decision-making bias: the missing ingredient in cell functional diversity [PDF]
Cell functional diversity is a significant determinant on how biological processes unfold. Most accounts of diversity involve a search for sequence or expression differences. Perhaps there are more subtle mechanisms at work. Using the metaphor of information processing and decision-making might provide a clearer view of these subtleties.
arxiv
New class of compounds - variators - are reprogramming substrate specificity of H4K12Ac, H4K16Ac and H4K20Ac epigenetic marks reading bromodomain of BPTF protein [PDF]
Previously reported [http://arxiv.org/abs/1506.06433] reprogramming of substrate specificity of H3K4Me3 epigenetic marks reading PHD domain of BPTF protein illustrates therapeutic potential of a new class of non-inhibitor small organic compounds - variators.
arxiv
Recent development on synthetic biological devices treating bladder cancer
Synthetic biology is an emerging field focusing on engineering genetic devices and biomolecular systems for a variety of applications from basic biology to biotechnology and medicine.
Zhicong Chen+4 more
doaj +1 more source
Partial restriction of genome expression — a component of its work reprogramming in regenerating liver of mammals [PDF]
M. Yu. Obolenskaya+3 more
openalex +1 more source
Xylella fastidiosa (Xf) is a global bacterial threat for a diversity of plants, including olive trees. However, current understanding of host responses upon Xf-infection is limited to allow early disease prediction, diagnosis, and sustainable strategies ...
Birgit Arnholdt-Schmitt+8 more
doaj +1 more source
The Function and Mechanism of Long Non-coding RNA-ATB in Cancers
Long non-coding RNAs (lncRNAs) are a class of transcriptional RNA molecules with a length of greater than 200 nucleotides that function as regulatory factors in many human diseases.
Huizhong Xiao+10 more
doaj +1 more source
Background Increased flux through both glycolytic and oxidative metabolic pathways is a hallmark of breast cancer cells and is critical for their growth and survival.
Sheree D. Martin, Sean L. McGee
doaj +1 more source